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Cord blood transplants made more accessible for thousands with blood cancers

NCT ID NCT01351545

Disease control Sponsor: Center for International Blood and Marrow Transplant Research Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study provides unlicensed cord blood units for transplant to children and adults with blood cancers, immune disorders, and other serious diseases. The goal is to see how well patients recover their white blood cells after the transplant. By making more cord blood units available, the study aims to help patients who cannot find a matching bone marrow donor.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 99,999 people

The number the study aims to enrol. It can still change while the study runs.

Start date

Oct 2011

Expected to finish

Oct 2041

An estimate. End dates often move.

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Recipients of unlicensed cryopreserved cord blood units who are being treated as U.S. transplant centers.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Disorders affecting the hematopoietic system that are inherited, acquired, or result from myeloablative treatment * Signed informed consent (and signed assent, if applicable) obtained prior to study enrollment * Pediatric and adult patients of any age Exclusion Criteria: * Patients who are receiving only licensed CBUs * Cord blood transplant recipients at international transplant centers * Patients who are enrolled on another IND protocol to access the unlicensed CBU(s) * Patients whose selected unlicensed CBU(s) will be more than minimally manipulated

Get updates

Get notified about this study

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Conditions

The condition(s) this trial relates to.

acquired aplastic anemia acute lymphoblastic leukemia acute myeloid leukemia aplastic anemia autoimmune disease chronic myelogenous leukemia, BCR-ABL1 positive disease hematopoietic and lymphoid system neoplasm Hodgkins lymphoma inborn errors of metabolism Leukemia, Myelogenous, Chronic, BCR-ABL Positive myelodysplastic/myeloproliferative neoplasm non-Hodgkin lymphoma plasma cell myeloma Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute lymphoblastic leukemia (ALL) Acute myelogenous leukemia (AML or anll) Autoimmune diseases Chronic myelogenous leukemia (CML) Disorders of the immune system Hematologic malignancies Histiocytic disorders Hodgkin lymphoma Inherited abnormalities of erythrocyte differentiation or function Inherited abnormalities of platelets Inherited disorders of metabolism Multiple myeloma/ plasma cell disorder (PCD) Myelodysplastic (MDS) / myeloproliferative (MPN) diseases Non-Hodgkin lymphoma Other acute leukemia Other leukemia Severe aplastic anemia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    119 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • AdventHealth Orlando

    RECRUITING

    Orlando, Florida, 32804, United States

  • Advocate Lutheran General Hospital

    TERMINATED

    Park Ridge, Illinois, 60068, United States

  • All Children's Hospital

    RECRUITING

    St. Petersburg, Florida, 33701, United States

  • Amarillo Blood and Marrow Transplant Program

    TERMINATED

    Amarillo, Texas, 79106, United States

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    RECRUITING

    Chicago, Illinois, 60614, United States

  • Arkansas Children's Hospital

    RECRUITING

    Little Rock, Arkansas, 72202, United States

  • Avera Transplant Institute

    RECRUITING

    Sioux Falls, South Dakota, 57105, United States

  • Banner MD Anderson Cancer Center

    RECRUITING

    Gilbert, Arizona, 85234, United States

  • Beth Israel Deaconess

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Cardinal Glennon Children's Medical Center

    RECRUITING

    St Louis, Missouri, 63104, United States

  • Children's Healthcare of Atlanta

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Children's Hospital Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

  • Children's Hospital and Research Center of Oakland

    ACTIVE_NOT_RECRUITING

    Oakland, California, 94609, United States

  • Children's Hospital at Montefiore

    RECRUITING

    The Bronx, New York, 10467, United States

  • Children's Hospital of Los Angeles

    RECRUITING

    Glendale, California, 91204, United States

  • Children's Hospital of Michigan

    RECRUITING

    Detroit, Michigan, 48201, United States

  • Children's Hospital of New Orleans/LSUHSC

    RECRUITING

    New Orleans, Louisiana, 70118, United States

  • Children's Hospital of Orange County (CHOC)

    RECRUITING

    Orange, California, 92868, United States

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • Children's Hospital of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

  • Children's Hospital of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • Children's Medical Center Dallas

    RECRUITING

    Dallas, Texas, 75235, United States

  • Children's Mercy Hospital and Clinics

    RECRUITING

    Kansas City, Missouri, 64108, United States

  • Children's National Medical Center

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

  • Childrens Hospital Medical Center of Akron

    RECRUITING

    Akron, Ohio, 44308, United States

  • Cincinnati Children's Hospital

    RECRUITING

    Cincinnati, Ohio, 45229, United States

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

  • Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195, United States

  • Cohen Children's Medical Center of New York

    RECRUITING

    New Hyde, New York, 11040, United States

  • Columbia University Medical Center - Morgan Stanley Children's Hospital

    RECRUITING

    New York, New York, 10032, United States

  • Cook Children's Hospital

    RECRUITING

    Fort Worth, Texas, 76104, United States

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Duke University Medical Center

    RECRUITING

    Durham, North Carolina, 27705, United States

  • Emory University Hospital

    TERMINATED

    Atlanta, Georgia, 30322, United States

  • Florida Center for Pediatric Cellular Therapy

    RECRUITING

    Orlando, Florida, 32804, United States

  • Fred Hutchinson Cancer Research Center

    RECRUITING

    Seattle, Washington, 98109, United States

  • Georgia Cancer Center at Augusta University Health

    RECRUITING

    Augusta, Georgia, 30912, United States

  • Greenebaum Cancer Center - University of Maryland

    WITHDRAWN

    Baltimore, Maryland, 21201, United States

  • H Lee Moffitt Cancer Center

    ACTIVE_NOT_RECRUITING

    Tampa, Florida, 33612, United States

  • Hackensack University Medical Center

    RECRUITING

    Hackensack, New Jersey, 07601, United States

  • Helen DeVos Children's Hospital

    RECRUITING

    Grand Rapids, Michigan, 49503, United States

  • Henry Ford Health System

    RECRUITING

    Detroit, Michigan, 48202, United States

  • Indiana Blood & Marrow Transplantation

    WITHDRAWN

    Beech Grove, Indiana, 46107, United States

  • Indiana University/Riley Hospital for Children

    RECRUITING

    Indianapolis, Indiana, 46202, United States

  • Johns Hopkins

    RECRUITING

    Baltimore, Maryland, 21287, United States

  • Kapiolani Medical Center for Women and Children

    RECRUITING

    Honolulu, Hawaii, 96813, United States

  • Karmanos Cancer Institute

    SUSPENDED

    Detroit, Michigan, 48201, United States

  • Levine Children's Hospital

    RECRUITING

    Charlotte, North Carolina, 28203, United States

  • Loma Linda University Cancer Center

    RECRUITING

    Loma Linda, California, 92350, United States

  • Loyola University Medical Center

    RECRUITING

    Maywood, Illinois, 60153, United States

  • M.D. Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital

    SUSPENDED

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic - Jacksonville

    WITHDRAWN

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic Arizona (adults)

    WITHDRAWN

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic Rochester

    ACTIVE_NOT_RECRUITING

    Rochester, Minnesota, 55905, United States

  • Medical City Dallas

    RECRUITING

    Dallas, Texas, 75230, United States

  • Medical College of Wisconsin

    ACTIVE_NOT_RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

  • Memorial Sloan-Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

  • Methodist Healthcare Blood and Marrow Transplant Center

    ACTIVE_NOT_RECRUITING

    Memphis, Tennessee, 38104, United States

  • Methodist Healthcare System of San Antonio/Texas Transplant Institute

    RECRUITING

    San Antonio, Texas, 78229, United States

  • Midwestern Regional Medical Center

    TERMINATED

    Zion, Illinois, 60099, United States

  • Mount Sinai Medical Center - New York

    RECRUITING

    New York, New York, 10029, United States

  • NIH/NCI

    ACTIVE_NOT_RECRUITING

    Bethesda, Maryland, 20892, United States

  • Nationwide Children's Hospital

    RECRUITING

    Columbus, Ohio, 43205, United States

  • Nemours - Alfred I. duPont Hospital for Children

    RECRUITING

    Brandywine, Delaware, 19803, United States

  • Nemours Children's Hospital - Mayo Jacksonville

    RECRUITING

    Jacksonville, Florida, 32207, United States

  • New York Presbyterian Hospital at Cornell

    RECRUITING

    New York, New York, 10021, United States

  • New York University Langone Medical Center

    RECRUITING

    New York, New York, 10016, United States

  • Nih/Nhlbi

    RECRUITING

    Bethesda, Maryland, 20892, United States

  • Nih/Niaid

    RECRUITING

    Bethesda, Maryland, 20892-1456, United States

  • Niklaus Children's Hospital

    RECRUITING

    Miami, Florida, 33155, United States

  • North Shore University Hospital

    RECRUITING

    Lake Sucess, New York, 11042, United States

  • Northside Hospital

    RECRUITING

    Atlanta, Georgia, 30342, United States

  • Northwestern Memorial Hospital

    RECRUITING

    Chicago, Illinois, 60611, United States

  • Oregon Health & Science University/Doernbecher Children's Hospital

    RECRUITING

    Portland, Oregon, 97239, United States

  • Orlando Health Arnold Palmer Hospital for Children

    RECRUITING

    Orlando, Florida, 32806, United States

  • Orlando Health Cancer Institute Bone Marrow Transplant and Cellular Therapy

    RECRUITING

    Orlando, Florida, 32806, United States

  • Penn State Milton S. Hershey Cancer Center

    RECRUITING

    Hershey, Pennsylvania, 17033, United States

  • Phoenix Children's Hospital

    RECRUITING

    Phoenix, Arizona, 85016, United States

  • Presbyterian St. Luke's/Colorado Blood Cancer Institute

    RECRUITING

    Denver, Colorado, 80218, United States

  • Rady Children's Hospital San Diego

    RECRUITING

    San Diego, California, 92123, United States

  • Robert Wood Johnson/Cancer Institute of New Jersey

    RECRUITING

    New Brunswick, New Jersey, 08901, United States

  • Roger Williams Medical Center

    SUSPENDED

    Providence, Rhode Island, 02908, United States

  • Roswell Park Cancer Institute

    RECRUITING

    Buffalo, New York, 14263, United States

  • Rush University Medical Center

    RECRUITING

    Chicago, Illinois, 60612, United States

  • Sarah Cannon BMT Program

    SUSPENDED

    Nashville, Tennessee, 37203, United States

  • Scripps Green Hospital

    RECRUITING

    La Jolla, California, 92037, United States

  • Southwest Cancer Treatment & Research Center

    WITHDRAWN

    Lubbock, Texas, 79415, United States

  • Spectrum Health

    RECRUITING

    Grand Rapids, Michigan, 49503, United States

  • St. Jude Childrens Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

  • St. Louis University Medical Center

    SUSPENDED

    St Louis, Missouri, 63110, United States

  • Stanford University Medical Center

    RECRUITING

    Stanford, California, 94304, United States

  • Stony Brook University Hospital

    RECRUITING

    Stony Brook, New York, 11794, United States

  • Strong Memorial Hospital/University of Rochester

    RECRUITING

    Rochester, New York, 14642-8704, United States

  • Sutter Medical Center

    RECRUITING

    Sacramento, California, 95816, United States

  • Texas Children's Hospital - Baylor Medical Center

    RECRUITING

    Houston, Texas, 77030, United States

  • The Arthur G. James Cancer Hospital/The Ohio State University Medical Center

    RECRUITING

    Columbus, Ohio, 43210, United States

  • The Children's Hospital of San Antonio

    RECRUITING

    San Antonio, Texas, 78207, United States

  • The Jewish Hospital

    WITHDRAWN

    Cincinnati, Ohio, 45230, United States

  • Tufts Medical Center

    RECRUITING

    Boston, Massachusetts, 02111, United States

  • Tulane Medical Center

    WITHDRAWN

    New Orleans, Louisiana, 70112, United States

  • UCLA

    RECRUITING

    Los Angeles, California, 90095, United States

  • UCSF (Peds)

    RECRUITING

    San Francisco, California, 94143, United States

  • UCSF (adults)

    ACTIVE_NOT_RECRUITING

    San Francisco, California, 94143, United States

  • Univeristy of Mississippi Medical Center

    RECRUITING

    Jackson, Mississippi, 39216, United States

  • University Hospitals Case Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35233, United States

  • University of Arizona Medical Center - Tucson

    RECRUITING

    Tucson, Arizona, 85224, United States

  • University of California San Diego

    RECRUITING

    La Jolla, California, 92093, United States

  • University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

  • University of Colorado Hospital

    RECRUITING

    Aurora, Colorado, 80045, United States

  • University of Florida Shands Medical Center

    RECRUITING

    Gainesville, Florida, 32610, United States

  • University of Illinois at Chicago

    RECRUITING

    Chicago, Illinois, 60612, United States

  • University of Iowa

    RECRUITING

    Iowa City, Iowa, 52242, United States

  • University of Kansas

    RECRUITING

    Westwood, Kansas, 66205, United States

  • University of Louisville Hospital - James Brown Cancer Center

    RECRUITING

    Louisville, Kentucky, 40202, United States

  • University of Massachusetts

    ACTIVE_NOT_RECRUITING

    Worcester, Massachusetts, 01655, United States

  • University of Miami (adult)

    ACTIVE_NOT_RECRUITING

    Miami, Florida, 33136, United States

  • University of Miami (peds)

    RECRUITING

    Miami, Florida, 33136, United States

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • University of Nebraska Medical Center

    RECRUITING

    Omaha, Nebraska, 68198-2168, United States

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

  • University of Oklahoma Health Science Center

    RECRUITING

    Oklahoma City, Oklahoma, 73103, United States

  • University of Pennsylvania/Thomas Jefferson

    RECRUITING

    Pittsburgh, Pennsylvania, 19104, United States

  • University of Pittsburgh Medical Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

  • University of Texas Southwestern Medical Center

    WITHDRAWN

    Dallas, Texas, 75390, United States

  • University of Utah

    RECRUITING

    Salt Lake City, Utah, 84132, United States

  • University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22908, United States

  • University of Wisconsin - Madison

    RECRUITING

    Madison, Wisconsin, 53792, United States

  • VA Puget Sound HCS

    SUSPENDED

    Seattle, Washington, 98108, United States

  • VA Tennessee Valley Healthcare System

    WITHDRAWN

    Nashville, Tennessee, 37212, United States

  • Vanderbilt University

    RECRUITING

    Nashville, Tennessee, 37232, United States

  • Virginia Commonwealth University

    RECRUITING

    Richmond, Virginia, 23227, United States

  • Wake Forest University

    WITHDRAWN

    Winston-Salem, North Carolina, 27157, United States

  • Washington University St. Louis

    RECRUITING

    St Louis, Missouri, 63110, United States

  • Washington University/St. Louis Children's Hospital

    RECRUITING

    St Louis, Missouri, 63110, United States

  • West Penn Hospital

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

  • West Virginia University

    RECRUITING

    Morgantown, West Virginia, 26506-8110, United States

  • Westchester Medical Center

    RECRUITING

    New York, New York, 10595, United States

  • Yale New Haven Hospital

    RECRUITING

    New Haven, Connecticut, 06510, United States

  • Zachary & Elizabeth Fisher Bone Marrow Transplant Program (Brooke Army Medical Center)

    RECRUITING

    Fort Sam Houston, Texas, 78234, United States

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Other studies related to the condition(s) this trial covers.