Cord blood collected from At-Risk newborns to advance sickle cell lab research
NCT ID NCT03876821
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study collected umbilical cord blood from 44 newborns whose mothers carry the sickle cell trait. The goal was to study the cells in the lab to better understand the disease and develop ways to modify and preserve them. No treatment was given; this was purely for research purposes.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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44 people
The number who actually took part.
- Started
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Oct 2019
- Finished
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Oct 2023
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study includes pregnant women, aged 18-45 years of age, carrying at least one HbS allele, and who are followed and giving birth at the maternity unit of the Centre Hospitalier Sud Francilien in Evry, France.
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Pregnant women, giving birth at CHSF and consenting to the collect and study of placental blood after delivery * Age 18 to 45 years * Biological testing of the participant includes hemoglobin electrophoresis and shows at least one HbS allele Exclusion Criteria: * Lack of written consent * Minors (not 18 years old) or under guardianship * Diseases : HIV, Hepatitis B, Hepatitis C or HTLV (Human T Leukemia Virus).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHSF
Corbeil-Essonnes, 91106, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can adding common pain drugs reduce morphine needs in sickle cell crises?
- Gene editing offers hope for a One-Time sickle cell cure
- Tiny biochip could reveal sickle cell severity
- Can a milder transplant cure sickle cell and thalassemia in adults?
- Can an antioxidant supplement calm sickle cell blood cells?