New study aims to uncover hidden lung risks in PRISm patients
NCT ID NCT06682832
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares exercise ability, muscle strength, blood vessel stiffness, and quality of life among three groups: people with COPD, those with a less-known condition called PRISm (Preserved Ratio Impaired Spirometry), and healthy individuals. Researchers will measure these factors using tests like a 6-minute walk and muscle oxygen monitoring. The goal is to better understand PRISm and how it differs from COPD, which could lead to better care and prevent progression.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better identify and manage people with PRISm, a lung condition that may progress to COPD.
- What could go wrong
- This is a small observational study (54 participants) that measures differences but does not test a treatment. Results may not apply to everyone with these conditions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 54 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
COPD and PRISm patients referred to the Cardiopulmonary Rehabilitation Unit for routine physiotherapy and rehabilitation will be included in the study. The group of healthy individuals will be formed by including the healthy siblings of the participants who are age and gender compatible with the COPD and PRISm groups, and the volunteers among the relatives and acquaintances of the researchers. 54 individuals will be included in the study.
- Ages
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40 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: PRISm group inclusion criteria; * Being \>40 years old, * Being diagnosed with PRISm, * Volunteering to participate in the study, * Not having any orthopaedic or neurological problems that may prevent participation in the measurements, * Co-operation with measurements Inclusion criteria for the COPD group; * Being \>40 years old, * Being diagnosed with COPD, * To be clinically stable, * Volunteering to participate in the study. Inclusion criteria for healthy individuals; * Being \>40 years old, * Volunteering to participate in the study, * No known chronic health problems, * To be able to co-operate with the measurements. Exclusion Criteria: PRISm group exclusion criteria; * Being diagnosed with COPD, * Severe orthopaedic, neurological and cardiac diseases * Not volunteering to participate in the study Exclusion criteria for COPD group; * Severe orthopaedic, neurological and cardiac diseases, * Being in COPD exacerbation period, * Not volunteering to participate in the study. Healthy individuals exclusion criteria; * Having a known chronic disease, * Not volunteering to participate in the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hacettepe University
RECRUITINGAnkara, 06560, Turkey (Türkiye)
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