Scientists dive deep into COPD at the Single-Cell level
NCT ID NCT07208123
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will analyze lung tissue from 150 people with and without COPD using single-cell sequencing. The goal is to understand the molecular changes that drive the disease. Researchers hope this knowledge will point toward new ways to diagnose or treat COPD in the future.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could reveal new targets for future COPD treatments by mapping the cellular changes in the disease.
- What could go wrong
- This is an observational study, not a treatment trial. It may not directly lead to new therapies, and findings may not apply to all COPD patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 150 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
150
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Receiving lung resection surgery at the hospital for any reason; * Diagnosed with COPD according to the 2024 GOLD guidelines; * Tissue samples that meet collection requirements and are either agreed to be collected or already preserved; Exclusion Criteria: * Improper preservation of pathological specimens, refusal to consent to sample collection, or incomplete clinical information; * Combined with other factors causing obstructive airflow limitation; * Diagnosed with asthma according to the GINA 2023 guidelines and with a history of asthma exacerbations within the past year; * Combined with Advanced lung cancer; * Receiving systemic immunosuppressive medications such as anti-rejection drugs;
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Renji Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, 200444, China
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