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New algorithm aims to catch COPD before It's too late

NCT ID NCT07223749

Diagnosis Sponsor: Wake Forest University Health Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Aug 28, 2026 · Updated 2 times

Summary

This study is testing a computer algorithm that uses health records to predict whether a person has COPD. Many people with COPD are not diagnosed until the disease is advanced, while others are wrongly told they have it. The goal is to see if the algorithm can correctly identify who truly has COPD, so patients can get the right care sooner.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a reliable way to diagnose COPD earlier and reduce misdiagnosis, helping patients get the right treatment sooner.
What could go wrong
This is an observational study testing an algorithm, not a treatment. The tool may not prove accurate enough in real-world settings, and results may not apply to all patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

425 people

The number who actually took part.

Started

Aug 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Data from the Wake Forest Baptist Medical Center in Winston Salem, NC and Lexington Medical Center in Lexington, NC were extracted from a common electronic health record system. Algorithm development included 15,065 patients who underwent pulmonary function testing in 2016-2022.

Ages

40 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * greater thank or equal to 40 years of age * 2 or more encounters in the health system * Previous Pulmonary Function Test (PFT) recorded in our Electronic Health Records (EHR) in the previous 5 years Exclusion Criteria: * cystic fibrosis * Alpha-1 Antitrypsin Deficiency (AAD)currently pregnant * History of a lung transplant or partial removal of the lung * significant chest wall deformity * neuromuscular disease that currently impacts the respiratory muscles * surgery requiring general anesthesia or an overnight stay in the hospital within the past 30 days

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COPD (chronic obstructive pulmonary disease)

Contacts and locations

Locations

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.