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COPD may weaken your ability to control leg muscles

NCT ID NCT06871670

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jul 08, 2026 · Updated 3 times

Summary

This study looked at whether people with COPD have trouble controlling their knee muscles during everyday tasks that require precise, gentle force. Researchers compared 36 participants (COPD patients and healthy volunteers) as they performed small, controlled leg contractions. The goal was to better understand how COPD affects muscle control, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

36 people

The number who actually took part.

Started

Mar 2025

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants enrolled in NEUROTIGUE study (NCT04028973)

Ages

40 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: COPD patients : * GOLD II - III or IV * FEV1 \<80% of predicted values * Men and women aged 40 years and over * French-speaking participant * BMI \<30 kg / m² * Stable condition (i.e. without exacerbation) for more than 15 days * Able to express their consent in writing prior to any participation in the study * Affiliates or beneficiaries of a social security * Minimum score of 26 on the MMSE questionnaire of 3 months or less Healthy volunteers : * Men and women aged 40 years and over * French-speaking participant * BMI \<30 kg / m² * No known chronic respiratory, cardiovascular, metabolic, renal or neuromuscular pathologies * Able to express their consent in writing prior to any participation in the study * Affiliates or beneficiaries of a social security * Minimum score of 26 on the MMSE questionnaire of 3 months or less For all participants : -Subject who has not objected to the reuse of data collected Exclusion Criteria: COPD patients : * Alcoholism, i.e. \> 21 glasses a week for men and \>14 glasses a week for women * Psychiatric pathologies or antecedent of behavioral disorders * Patients treated with oral or systemic corticosteroids (\> 0.5 mg / kg / day for \> 7 days) * Contraindication to the application of a magnetic field (i.e. right hip arthroplasty, pelvic / abdominal surgeries) * Severe vision or hearing problems not corrected * Patient oxygen dependent * Patients in exclusion period from another research protocol * Pregnant women (known pregnancy) or lactating women * Patient deprived of liberty by a judicial or administrative decision * Patient subject to a legal protection measure or unable to express their consent * Patient who is not sufficiently fluent in reading and understanding the French language to be able to consent to participate in the study * Patient unable to follow study procedures and to respect visits throughout the study period * Person with a medical history that, in the opinion of the investigator, could interfere with the results of the study * Any condition that, in the opinion of the investigator, could increase and compromise the safety of the person in the event that he / she participates in the study * Any other reason that, in the opinion of the investigator, could interfere with the evaluation of the aims of the study Healthy volunteers: * Alcoholism, i.e. \> 21 glasses a week for men and \>14 glasses a week for women * Psychiatric pathologies or antecedent of behavioral disorders * Patients treated with oral or systemic corticosteroids (\> 0.5 mg / kg / day for \> 7 days) * Contraindication to the application of a magnetic field (i.e. right hip arthroplasty, pelvic / abdominal surgeries) * Severe vision or hearing problems not corrected * Subjects in exclusion period from another research protocol * Pregnant women (known pregnancy) or lactating women * Regular physical activity with a frequency greater than 3 sessions per week * Participant deprived of liberty by a judicial or administrative decision * Participant subject to a legal protection measure or unable to express their consent * Participant who is not sufficiently fluent in reading and understanding the French language to be able to consent to participate in the study * Participant unable to follow study procedures and to respect visits throughout the study period * Person with a medical history that, in the opinion of the investigator, could interfere with the results of the study * Any condition that, in the opinion of the investigator, could increase and compromise the safety of the person in the event that he / she participates in the study * Any other reason that, in the opinion of the investigator, could interfere with the evaluation of the aims of the study

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Université de Toulon, laboratoires Laboratoire J-AP2S

    Toulon, VAR, 83000, France

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Other studies related to the condition(s) this trial covers.