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New drug targets Hard-to-Treat cancers with PTEN mutation

NCT ID NCT06400238

First seen Oct 31, 2025 · Last updated May 25, 2026 · Updated 29 times

Summary

This study tests a drug called copanlisib in 35 adults with advanced or treatment-resistant cancers that have a specific change in the PTEN gene. The drug blocks a protein that helps cancer cells grow, aiming to shrink tumors or stop them from spreading. The main goal is to see how many patients respond to treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.