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Does continuous blood pressure monitoring during surgery prevent organ failure?

NCT ID NCT05496322

Knowledge-focused Sponsor: University of Messina Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether using continuous non-invasive blood pressure monitoring during surgery could reduce the risk of organ failure after surgery, compared to standard intermittent monitoring. Over 1,200 adults having non-cardiac surgery took part. The main focus was on preventing heart injury and kidney damage in the first week after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Continuous non-invasive blood pressure monitoring device
What this could lead to
If it works, this could show that continuous blood pressure monitoring during surgery helps prevent heart and kidney damage afterward.
What could go wrong
This is a completed study, but the results may not show a clear benefit. The approach is still being tested, and individual patient factors can affect outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

1,267 people

The number who actually took part.

Started

Jan 2023

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All adult (age ≥18 years) patients scheduled for elective non-cardiac surgery in participating centers * Surgical case planned with non invasive blood pressure monitoring according to local clinical practice or policies. Exclusion Criteria: * Missing of preoperative serum creatinine during 30 days prior surgery * Preoperative dialysis * Chronic kidney disease (eGFR \< 60ml/min Cockcroft-Gault equation) * Surgical procedure lasting less than 60 min * Planned use of permissive hypotension * Urological procedures (including nephrectomy and renal transplantation) * Refusal to give informed consent

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Conditions

The condition(s) this trial relates to.

Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blood pressure determination Hemodynamic monitoring Postoperative complications

Contacts and locations

Locations

  • A.O.U. G.Martino - University of Messina

    Messina, 98100, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.