Which contact lens feels better? study puts two brands to the test
NCT ID NCT06749496
First seen Jun 27, 2026 · Last updated Sep 03, 2026 · Updated 4 times
Summary
This study tested two types of daily disposable contact lenses for people with astigmatism to see which one felt more comfortable. 134 adults wore each lens for one week and rated their comfort. The goal was to find out which lens provided longer-lasting comfort and a better overall experience.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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134 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Mar 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 39 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Potential subjects must satisfy all of the following criteria to be enrolled in the study: The subject must: 1. Read, understand, and sign the STATEMENT OF INFORMED CONSENT and receive a fully executed copy of the form. 2. Appear able and willing to adhere to the instructions set forth in this clinical protocol. 3. Be between 18 and 39 (inclusive) years of age at the time of screening. 4. By self-report, habitually wear soft contact lenses in both eyes in a daily reusable or daily disposable wear modality (i.e., not extended wear modality). Habitual wear is defined as a minimum of 6 hours of wear per day, for a minimum of 2 days per week during the past four weeks. 5. Possess a wearable pair of spectacles that provide correction for distance vision. 6. In both eyes, have refractive error suitable for correction with the range of toric contact lens powers available in this study: 6.1 Sphere powers (DS) -1.50 through -4.00 (inclusive) in 0.25 steps 6.2 Cylinder powers (DC) -0.75 and -1.25 6.3 Axes (°) 170, 180, 10, 80, 90 and 100 7. Have best corrected monocular distance visual acuity of 20/25 or better in each eye. Potential subjects who meet any of the following criteria will be excluded from participating in the study: The subject must not: 1. Be currently pregnant or lactating. 2. Be diabetic. 3. Be currently using any ocular medications or have any ocular infection of any type. 4. By self-report, have any ocular or systemic disease, allergies, infection, or use of medication that might contraindicate or interfere with contact lens wear, or otherwise compromise study endpoints, including infectious disease (e.g., hepatitis, tuberculosis), contagious immunosuppressive disease (e.g., Human Immunodeficiency Virus \[HIV\]), autoimmune disease (e.g., rheumatoid arthritis, Sjögren's syndrome), or history of serious mental illness or seizures. See section 9.1 for additional details regarding excluded systemic medications. 5. Have habitually worn rigid gas permeable (RGP) lenses, orthokeratology lenses, or hybrid lenses (e.g., SynergEyes, SoftPerm) within the past 6 months. 6. Be currently wearing monovision or multifocal contact lenses. 7. Be currently wearing lenses in an extended wear modality. 8. Have a history of strabismus or amblyopia. 9. Be an employee (e.g., Investigator, Coordinator, Technician) or immediate family member of an employee (including partner, child, parent, grandparent, grandchild or sibling of the employee or their spouse) of the clinical site. 10. Have participated in a contact lens or lens care product clinical trial within 7 days prior to study enrollment. 11. Have clinically significant (grade 3 or higher on the FDA grading scale) slit lamp findings (e.g., corneal edema, neovascularization or staining, tarsal abnormalities or bulbar injection) or other corneal or ocular disease or abnormalities that contraindicate contact lens wear or may otherwise compromise study endpoints (including entropion, ectropion, chalazia, recurrent styes, glaucoma, history of recurrent corneal erosions, aphakia, moderate or above corneal distortion, herpetic keratitis). 12. Have fluctuations in vision due to clinically significant dry eye or other ocular conditions. 13. Have had or have planned (within the study period) any ocular or intraocular surgery (e.g., radial keratotomy, PRK, LASIK, iridotomy, retinal laser photocoagulation, etc.).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Birmingham Vision Care
Bloomfield Hills, Michigan, 48301, United States
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Botetourt Eyecare, LLC
Salem, Virginia, 24153, United States
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Complete Eye Care of Medina
Medina, Minnesota, 55340, United States
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Kannarr Eye Care - 101 North Broadway
Pittsburg, Kansas, 66762, United States
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Maitland Vision Center - North Orlando Ave
Maitland, Florida, 32751, United States
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Omega Vision Center
Longwood, Florida, 32779, United States
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Optometry Group, PLLC
Memphis, Tennessee, 38111, United States
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Procare Vision Centers
Granville, Ohio, 43023, United States
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Professional Vision Care Inc. - Westerville
Westerville, Ohio, 43081, United States
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Sacco Eye Group
Vestal, New York, 13850, United States
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Stam & Associates Eye Care
Jacksonville, Florida, 32256, United States
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Tyler Eye Associates
Tyler, Texas, 75703, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Two toric lenses go head to head in vision test
- Can glasses that slow nearsightedness also reshape a Child's astigmatism?
- Can newer cataract lenses keep vision clear for years?
- A simple fix for myopia could change education for millions
- Can eye shape predict which contact lens stays put?