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Lung cancer combo shows promise in slowing disease progression

NCT ID NCT04765059

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 36 times

Summary

This study tests whether adding the targeted drug osimertinib to standard chemotherapy can help people with a certain type of advanced lung cancer (EGFR-mutant non-small cell lung cancer) whose disease has gotten worse after initial osimertinib treatment. About 98 participants will receive either chemotherapy plus osimertinib or chemotherapy plus a placebo. The main goal is to see if the combination delays cancer growth or spread.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Silver Spring, Maryland, 20910, United States

  • Research Site

    Boston, Massachusetts, 02114, United States

  • Research Site

    Beijing, 100005, China

  • Research Site

    Beijing, 100142, China

  • Research Site

    Ganzhou, 341099, China

  • Research Site

    Guangzhou, 510080, China

  • Research Site

    Jinan, 250013, China

  • Research Site

    Shenyang, 110001, China

  • Research Site

    Tianjin, 300060, China

  • Research Site

    Zhengzhou, 450008, China

  • Research Site

    Berlin, 12351, Germany

  • Research Site

    Cologne, 50937, Germany

  • Research Site

    Cologne, 51109, Germany

  • Research Site

    Hanover, 30625, Germany

  • Research Site

    München, D-80336, Germany

  • Research Site

    Beersheba, 84101, Israel

  • Research Site

    Jerusalem, 9103102, Israel

  • Research Site

    Jerusalem, 9112001, Israel

  • Research Site

    Kfar Saba, 4428164, Israel

  • Research Site

    Tel Aviv, 6423906, Israel

  • Research Site

    Tel Litwinsky, 52621, Israel

  • Research Site

    Florence, 50134, Italy

  • Research Site

    Meldola, 47014, Italy

  • Research Site

    Messina, 98158, Italy

  • Research Site

    Naples, 80131, Italy

  • Research Site

    Padova, 35128, Italy

  • Research Site

    Roma, 00168, Italy

  • Research Site

    Terni, 05100, Italy

  • Research Site

    Verona, 37124, Italy

  • Research Site

    Alicante, 03010, Spain

  • Research Site

    Barcelona, 08907, Spain

  • Research Site

    Córdoba, 14004, Spain

  • Research Site

    León, 24071, Spain

  • Research Site

    Madrid, 28040, Spain

  • Research Site

    Málaga, 29010, Spain

  • Research Site

    Murcia, 30008, Spain

  • Research Site

    Oviedo, 33011, Spain

  • Research Site

    Palma de Mallorca, 07010, Spain

  • Research Site

    Seville, 41013, Spain

  • Research Site

    Valencia, 46010, Spain

Conditions

Explore the condition pages connected to this study.