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Which ventilator mode is gentler on the lungs during surgery?

NCT ID NCT07670494

Knowledge-focused Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 4 times

Summary

This study looks at two different ways a breathing machine (ventilator) can support patients during gallbladder surgery. One mode lowers peak airway pressure, but doctors suspect it might actually deliver more total energy to the lungs. Researchers will measure the energy transferred to the lungs in 80 patients using both modes to see which is truly gentler. The goal is to find safer ventilation practices to reduce the risk of lung irritation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If this study shows one ventilator mode is gentler on the lungs, it could guide safer breathing support during surgery.
What could go wrong
This is a small, early-stage study (80 people) that only measures a monitor reading, not actual patient outcomes like lung injury. Results may not apply to other surgeries or patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients undergoing elective laparoscopic cholecystectomy surgery. * Patients between 18 and 75 years of age. * American Society of Anesthesiologists (ASA) physical status I, II or III. * Body Mass Index (BMI) between 18.5 and 35 kg/m². * Voluntary written informed consent for participation. Exclusion Criteria: * History of significant chronic obstructive pulmonary disease (COPD) or asthma. * Previous lung resection or major thoracic surgery. * Heavy smokers (more than 20 cigarettes per day). * Presence of spontaneous breathing effort during mechanical ventilation. * Conversion from laparoscopic surgery to open surgery during the procedure. * Emergency surgery cases. * Known pregnancy.

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Conditions

The condition(s) this trial relates to.

Ventilator-Induced Lung Injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Laparoscopic cholecystectomy Mechanical ventilation Ventilator induced lung injury

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Dr. Abdurrahman Yurtaslan Ankara Oncology Hospital

    RECRUITING

    Yenimahalle, Ankara, 06370, Turkey (Türkiye)

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