Which prolapse repair works best? new study compares One-Sided vs. Two-Sided surgery
NCT ID NCT07552337
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 160 women with pelvic organ prolapse who had a hysterectomy and then one of two surgical repairs. The goal was to see if repairing one side or both sides of the supporting ligaments works better and is safer. Results may help doctors choose the best approach for each patient.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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160 people
The number who actually took part.
- Started
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Jan 2023
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female patients aged 18 years and older * Diagnosis of pelvic organ prolapse requiring surgical treatment * Planned vaginal hysterectomy with high uterosacral ligament suspension * Ability to provide informed consent Exclusion Criteria: * Previous pelvic organ prolapse surgery involving apical support * Presence of pelvic malignancy * Active pelvic infection * Severe comorbidities contraindicating surgery * Pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Saglik Bilimleri University Gazi Yasargil Training and Research Hospital
Diyarbakır, 21000, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can strength training steady the walk and strengthen the pelvic floor after menopause?
- Can a biological mesh improve pelvic floor surgery?
- Can targeted exercises ease mild pelvic organ prolapse without surgery?
- AI may predict which pelvic floor therapy works best
- Can a small pressure drop make prolapse surgery less painful?
- Could a simple surgical step make hysterectomies safer?