Keyhole vs scope: which stone surgery wins?
NCT ID NCT07197385
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compared two common surgeries for removing large kidney stones stuck in the upper ureter: ureteroscopic lithotripsy (URS) and laparoscopic ureterolithotomy (LU). Fifty-six adults with a single stone between 10-20 mm were randomly assigned to one procedure. Researchers measured operation time, hospital stay, pain, complications, and how completely stones were removed after four weeks to determine which method is safer and more effective.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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56 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Jun 2025
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients of both genders with age ≥ 18 years. * Patients with a duration of symptoms for more than 1 month. * Patients having a unilateral single stone of 10 mm to 20 mm in diameter, located between the ureteropelvic junction and the upper border of the sacroiliac joint (upper ureteral stone). Exclusion Criteria: * Patients with a history of ipsilateral ureteric surgeries, previous open abdominal surgeries, bleeding disorders and pregnancy. * Before surgery, patients had a positive urine culture, fever (37.60c) and leukocytosis \> 12.000 per microliter. * Patients having solitary kidney and co-morbidities e.g., cardiovascular, Liver, respiratory illnesses, or serum creatinine \>1.5 mg/dl. * Horseshoe kidneys, pelvic kidneys, pyonephrosis, ureteropelvic junction blockage, and ureteral stricture. * Patients with unsuitable for general anesthesia.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Lahore General Hospital, Lahore
Lahore, Punjab Province, 54000, Pakistan
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Other studies related to the condition(s) this trial covers.
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