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Timing of tooth extraction may speed up braces treatment

NCT ID NCT07445321

Knowledge-focused Sponsor: Dow University of Health Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 34 people getting braces who needed all four first premolars removed. It compared how fast and how much the gaps closed when teeth were pulled just before braces (fresh sites) versus waiting for the gums to heal first (healed sites). The goal is to help orthodontists decide the best time for extractions to make treatment more efficient.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help orthodontists decide the best time to extract teeth to shorten treatment duration.
What could go wrong
This is a small, completed trial with only 34 participants, so results may not apply to everyone. It does not test a new treatment, just compares timing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

34 people

The number who actually took part.

Started

Feb 2023

Finished

Feb 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18-35 years. * Patients undergoing fixed appliance treatment. * Good oral hygiene and periodontal support. * Patients with all first premolar's extraction treatment plan. * Atraumatic extraction. Exclusion Criteria: * History of previous orthodontic treatment * Systemic diseases like diabetes, hypertension etc * Any bone pathology or taking medicines like bisphosphonates * Patients with clefts or any syndromic condition. * Patients with old extraction socket.

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Conditions

The condition(s) this trial relates to.

Bicuspid Aortic Valve Disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Orthodontic extraction

Contacts and locations

Locations

  • Dr Ishrat ul Ebad Khan Institute of Oral Health Sciences

    Karachi, Sindh, 75300, Pakistan