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Which skin glue is gentler? new study puts three to the test

NCT ID NCT05492721

Symptom relief Sponsor: The University of Texas Health Science Center, Houston Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested three different skin glues (Dermabond, Swiftset, and Liquiband) used to close small incisions after laparoscopic or robotic abdominal surgery. 180 adults each received two different glues on opposite sides of their incisions. The main goal was to see which glue caused less contact dermatitis (redness or rash). The trial is complete, and results will help surgeons choose the gentler option.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
skin glue (2-Octylcyanoacrylate and N-butyl-2-cyanoacrylate)
What this could lead to
If one glue causes less skin irritation, it could become the preferred choice for closing small surgical cuts, reducing discomfort and rash.
What could go wrong
This is a small, completed trial focused on a minor side effect (contact dermatitis). The results may not apply to all surgeries or patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

180 people

The number who actually took part.

Started

Jun 2022

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 or older * undergoing an elective laparoscopic or robotic abdominal surgery Exclusion Criteria: * Patients unlikely to follow-up (live out of state, unable to be reached by phone or email) * Patients with a known allergy to 2-Octylcyanoacrylate or N-butyl-2-cyanoacrylate.

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Conditions

The condition(s) this trial relates to.

contact dermatitis dermatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dermatitis, contact

Contacts and locations

Locations

  • Memorial Hermann

    Houston, Texas, 77030, United States