Study tests best ventilator settings for laparoscopic surgery patients
NCT ID NCT06625099
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 101 patients having laparoscopic (keyhole) abdominal surgery to compare two different levels of positive pressure used by the breathing machine. One group got a standard low pressure, the other got an 'optimum' pressure tailored to their lungs. The goal was to see which setting led to better oxygen levels and less strain on the lungs. The study is already completed, and the results may help guide future ventilator use during surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Positive end-expiratory pressure (PEEP) levels during mechanical ventilation
- What this could lead to
- If it works, this could help doctors choose the best ventilator settings during laparoscopic surgery to improve patient breathing and reduce lung strain.
- What could go wrong
- This is a small, completed study focused on short-term measurements during surgery, not long-term outcomes. Results may not apply to all patients or surgeries.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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101 people
The number who actually took part.
- Started
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Sep 2024
- Finished
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Oct 2025
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients scheduled to undergo laparoscopic cholecystectomy in the operating rooms of Kocaeli City Hospital will constitute the study universe.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * within the appropriate age range * agreeing to participate in the study * again receiving lancetesthesia * volume controlled ventilation * no known lung disease * no known coronary artery disease * ASA class 1-2 patients Exclusion Criteria: * . Patients who do not want to be included in the study will not be included * Patients with intraoperative deep hypotension (mean arterial pressure \<50) will be excluded. * Those who develop intraoperative hypothermia or have other anesthesia complications will be excluded. * Patients who will not be extubated postoperatively will be excluded from the study. * Those with neurological diseases or those using psychiatric medications will also be excluded from the study.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Kocaeli City Hospital
Kocaeli, Izmıt, 41100, Turkey (Türkiye)
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