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Nerve block showdown: which injection eases pain and protects breathing after lung surgery?

NCT ID NCT07655336

Symptom relief Sponsor: Ferit Yetik Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of nerve blocks—SPSIP and RISS—given before lung surgery to control pain and help breathing afterward. Eighty-four adults having a specific type of lung surgery will receive one of the two blocks. Researchers will measure pain at the chest tube site, overall pain, opioid use, and breathing function to see which block offers better recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nerve block (local anesthetic injection)
What this could lead to
If one block works better, it could mean less pain and better breathing after lung surgery, leading to faster recovery.
What could go wrong
This is a small, early-stage comparison. The results may not apply to all surgeries, and nerve blocks carry rare risks like infection or bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 84 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients scheduled for elective biportal video-assisted thoracoscopic surgery (VATS) with lung parenchyma-preserving thoracic procedures under general anesthesia * American Society of Anesthesiologists (ASA) physical status I-III * Age between 18 and 75 years * Provision of written informed consent Exclusion Criteria: * Use of anticoagulant or antiplatelet therapy * Bleeding diathesis * Known allergy to local anesthetics * Infection at the planned block site * Severe chronic pulmonary disease or advanced respiratory failure (e.g., severe COPD or restrictive lung disease) * Cognitive impairment preventing reliable NRS assessment * Pregnancy or lactation * Chronic opioid use (regular use for ≥3 months) * Severe hepatic or renal failure * Refusal to participate * Technical failure or unsuccessful regional block * Conversion to open thoracotomy during surgery

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain Thoracic surgery

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Bursa City Hospital

    RECRUITING

    Bursa, Nilüfer, 16100, Turkey (Türkiye)

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