Nerve zap showdown: one side or both for bladder relief?
NCT ID NCT01558856
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether stimulating nerves on one side or both sides of the body works better for people with overactive bladder that hasn't improved with standard treatments. 55 adults were randomly assigned to receive either unilateral or bilateral nerve stimulation. The goal was to see if symptoms like frequent urination and sudden urges improved by at least half after one month.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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55 people
The number who actually took part.
- Started
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Oct 2012
- Finished
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Jan 2018
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * The patient must have given his/her informed and signed consent * The patient must be insured or beneficiary of a health insurance plan * The patient is available for 1 month of follow-up * The patient understands and reads French * The patient has symptoms of overactive bladder resistant to first-line treatments (physiotherapy, anticholinergics) * The patient suffers from an overactive bladder confirmed by a urodynamic panel * The patient suffers from an overactive bladder unassociated with bladder obstruction as confirmed by flowmetry * The patient has primary (idiopathic) overactive bladder primary with normal urinalysis, abdominal and pelvic ultrasound, urine cytology + / - cystoscopy * The patient has no bleeding disorders, or the disorder is properly controlled after treatment Exclusion Criteria: * The patient is participating in another study * The patient is in an exclusion period determined by a previous study * The patient is under judicial protection, under tutorship or curatorship * The patient refuses to sign the consent * It is impossible to correctly inform the patient * The patient is pregnant, parturient, or breastfeeding * Overactive bladder associated with bladder obstruction as determined by flowmetry * Overactive bladder unconfirmed by urodynamic panel * Overactive bladder secondary to another condition: * vesical: urolithiasis, bladder polyp, interstitial cystitis * pelivienne: tumor or inflammatory * neurological: multiple sclerosis, brain tumor, epilepsy * the patient has an uncorrectable bleeding disorder
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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APHP - Groupe Hospitalier Pitié-Salpetrière
Paris, 75651, France
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CHRU de Toulouse - Hôpital de Rangueil
Toulouse, 31059, France
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CHU de Nantes - Hôtel Dieu
Nantes, 44093, France
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CHU de Nîmes - Hôpital Universitaire Carémeau
Nîmes, 30029, France
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CHU de Rouen - Hôpital Charles Nicolle
Rouen, 76031, France
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Clinique Beau Soleil
Montpellier, 34070, France
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Other studies related to the condition(s) this trial covers.
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