New nerve block combo may spare breathing while killing shoulder pain
NCT ID NCT05444517
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two ways to numb the shoulder after surgery: the standard interscalene block and a combination of two other blocks (infraclavicular and anterior suprascapular). The goal was to see if the combination could provide equal pain relief without causing temporary diaphragm paralysis, a common side effect of the standard block. Fifty adults having arthroscopic shoulder surgery took part, and their pain levels were compared at rest after surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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50 people
The number who actually took part.
- Started
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Jun 2023
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients undergoing arthroscopic shoulder surgery * American Society of Anesthesiologists classification 1-3 * Body mass index between 20 and 35 kg/mt2 Exclusion Criteria: * Adults who are unable to give their own consent * Pre-existing neuropathy (assessed by history and physical examination) * Coagulopathy (assessed by history and physical examination and, if deemed clinically necessary, by blood work up i.e. platelets ≤ 100, International Normalized Ratio ≥ 1.4 or prothrombin time ≥ 50) * Obstructive or restrictive pulmonary disease (assessed by history and physical examination) * Renal failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work up i.e. creatinine ≥ 100) * Hepatic failure (assessed by history and physical examination and, if deemed clinically necessary, by blood work up i.e. transaminases ≥ 100) * Allergy to local anesthetics (LAs) * Pregnancy * Prior surgery in the neck or infraclavicular region * Chronic pain syndromes requiring opioid intake at home
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospital Clínico Universidad de Chile
Santiago, Santiago Metropolitan, Chile
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Other studies related to the condition(s) this trial covers.
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