Which intubation method keeps heart rate and blood pressure more stable?
NCT ID NCT06487988
First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 2 times
Summary
This study compares two methods of placing a breathing tube during general anesthesia without using opioid painkillers. The goal is to see which method—fiberoptic or direct laryngoscopy—causes less change in heart rate and blood pressure. Researchers will study 90 adults aged 18 to 55 having elective surgery. They will also check how long intubation takes and if patients have sore throat, hoarseness, or airway injury afterward.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If fiberoptic intubation proves more stable, it could guide safer anesthesia practices for patients who cannot receive opioids.
- What could go wrong
- This is a small, early-stage study (90 participants) focused on short-term vital signs, not long-term outcomes. Results may not apply to all patients or settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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68 people
The number who actually took part.
- Started
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Sep 2024
- Finished
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Jun 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 55 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ASA (American Society of Anesthesiologists) physical status I and II * Range age of 18-55 years' old * Scheduled for elective surgery under general anesthesia. Exclusion Criteria: * History of cardiovascular diseases. * History of lung disease. * Hypertensive patient (BP\> 140/90) * Patient taking medications that affect blood pressure and heart rate * Morbid obesity (BMI \>30) * Severe GERD * Predicted difficult airway (Short TMD \<6 cm, Upper li bite test grade III, Mallampati score \>III) * Neck instability * Patient planned to receive rapid sequence intubation * Patient refusal to participate * History of difficult intubation/ ventilation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Christian Rouphael
Beirut, Lebanon
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