Which CML drug works best? new trial pits imatinib against dasatinib

NCT ID NCT00070499

Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Aug 27, 2026 · Updated 6 times

Summary

This phase 2 trial compares two standard CML drugs—imatinib (Gleevec) at two different doses and dasatinib (Sprycel)—in 406 newly diagnosed patients with chronic phase CML. The main goal is to see which treatment leads to the best molecular response after 12 months, meaning a very low level of cancer cells. Researchers also track blood count recovery and overall survival. This study aims to find the most effective starting treatment for this type of leukemia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: imatinib mesylate and dasatinib
What this could lead to: If successful, this could help identify which drug or dose works best for newly diagnosed CML patients, improving long-term disease control.
What could go wrong: This is a phase 2 study, so results are preliminary. The drugs may not show clear differences, and side effects like fluid retention or low blood counts are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

406 people

The number who actually took part.

Started

Aug 2004

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

A government research agency

The lead sponsor is the US National Institutes of Health.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients must have CML in chronic phase based on bone marrow aspiration and biopsy and peripheral blood counts obtained within 28 days before registration * Patients must be registered on this study within 180 days after the date of first being diagnosed with CML, based on a cytogenetic or molecular analysis of peripheral blood or bone marrow, demonstrating the presence of the Philadelphia chromosome or variants of the (9;22) translocation or testing positive for Bcr-Abl by real time-polymerase chain reaction (RT-PCR); patients may have secondary chromosomal abnormalities in addition to the Philadelphia chromosome and remain eligible * Patients must have Zubrod performance status 0-2 * Patients must not have received prior treatment for CML with the exception of hydroxyurea and/or anagrelide * Patients must not have received any prior chemotherapy regimen for peripheral blood stem cell mobilization; (prior collection of unmobilized peripheral blood stem cells is permitted) * Serum bilirubin =\< 2.0 x the institutional upper limit of the normal (IULN) * Serum glutamic oxaloacetic transaminase (SGOT)/aspartate aminotransferase (AST) or serum glutamate pyruvate transaminase (SGPT)/alanine transaminase (ALT) =\< 2.0 x the IULN * Patients (Southwestern Oncology Group \[SWOG\] institutions only) must be registered on SWOG-9007, "Cytogenetic Studies in Leukemia Patients;" collection of the pretreatment bone marrow specimen must be completed within 28 days prior to registration; the pretreatment bone marrow specimen must be submitted to an approved Southwest Oncology Group Cytogenetics Laboratory for cytogenetic analysis as described, and an aliquot of the bone marrow (or peripheral blood if the marrow aspiration is a dry tap) must be submitted for fluorescent in situ hybridization (FISH) analysis; note that protocol SWOG-9007 also requires submission of bone marrow specimens at the time of progression to the accelerated or blastic phase of CML or the loss of complete hematologic response and every six months while the patient is on this study * Patients (SWOG institutions only) must be registered on S9910, "Leukemia Centralized Reference Laboratories and Tissue Repositories, Ancillary;" specimens of peripheral blood and bone marrow must be submitted to the Southwest Oncology Group Lymphoid Leukemia and CML Centralized Laboratory in Seattle, Washington; collection of pretreatment blood and marrow specimens must be completed within 28 days prior to registration; note that this study also requires submission of peripheral blood and bone marrow specimens at various times after entry into the study * Patients must not have undergone major surgery within 28 days before registration, and must have fully recovered from any other prior major surgery * Patients must not be pregnant or nursing; women/men of reproductive potential must have agreed to use an effective contraceptive method * No other prior malignancy is allowed except for the following: adequately treated basal cell or squamous cell skin cancer, cervical carcinoma in situ, adequately treated stage I or II cancer from which the patient is currently in complete remission, or any other cancer from which the patient has been disease-free for five years * Patients must have an electrocardiogram (ECG) within 42 days prior to registration, and must not have any of the following cardiac symptoms prior to entry on study: * Uncontrolled angina, congestive heart failure or myocardial infarction (MI) within 6 months of study entry * Diagnosed or suspected congenital long QT syndrome * Any history of clinically significant ventricular arrhythmias (such as ventricular tachycardia, ventricular fibrillation, or Torsades de pointes) * Prolonged corrected QT (QTc) interval on pre-entry electrocardiogram (\> 450 msec) * Uncontrolled hypertension * Patients must not have a history of significant bleeding disorder unrelated to cancer, including: * Congenital bleeding disorders (e.g., von Willebrand's disease) * Acquired bleeding disorder within one year (e.g., acquired anti-factor VIII antibodies) * All patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines * At the time of patient registration, the treating institution's name and identification (ID) number must be provided to the Data Operations Center in Seattle in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered into the data base

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Conditions

The condition(s) this trial relates to.

chronic myelogenous leukemia, BCR-ABL1 positive Leukemia, Myelogenous, Chronic, BCR-ABL Positive

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic myeloid leukemia, BCR-ABL1 positive

Contacts and locations

Locations

AMG Libertyville - Oncology

Libertyville, Illinois, 60048, United States
Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Adena Regional Medical Center

Chillicothe, Ohio, 45601, United States
Adirondack Cancer Center

Glens Falls, New York, 12801, United States
AdventHealth Shawnee Mission

Shawnee Mission, Kansas, 66204, United States
Allan Blair Cancer Centre

Regina, Saskatchewan, S4T 7T1, Canada
Allegiance Health

Jackson, Michigan, 49201, United States
AnMed Health Hospital

Anderson, South Carolina, 29621, United States
Ascension Via Christi Hospitals Wichita

Wichita, Kansas, 67214, United States
Aspirus Cancer Care - Stevens Point

Stevens Point, Wisconsin, 54481, United States
Aspirus Cancer Care-Rhinelander-James Beck Cancer Center

Rhinelander, Wisconsin, 54501, United States
Associates In Womens Health

Wichita, Kansas, 67208, United States
Atrium Medical Center-Middletown Regional Hospital

Franklin, Ohio, 45005-1066, United States
Audie L Murphy VA Hospital

San Antonio, Texas, 78229, United States
Aultman Health Foundation

Canton, Ohio, 44710, United States
Avera Cancer Institute

Sioux Falls, South Dakota, 57105, United States
Avera McKennan Hospital and University Health Center

Sioux Falls, South Dakota, 57117-5045, United States
Baptist MD Anderson Cancer Center

Jacksonville, Florida, 32207, United States
Baton Rouge General Medical Center

Baton Rouge, Louisiana, 70806, United States
Beacon Kalamazoo

Kalamazoo, Michigan, 49048, United States
Beebe Medical Center

Lewes, Delaware, 19958, United States
Benefis Sletten Cancer Institute

Great Falls, Montana, 59405, United States
Berdeaux, Donald MD (UIA Investigator)

Great Falls, Montana, 59405, United States
Billings Clinic Cancer Center

Billings, Montana, 59101, United States
Blanchard Valley Hospital

Findlay, Ohio, 45840, United States
Bozeman Health Deaconess Hospital

Bozeman, Montana, 59715, United States
Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
Bronson Battle Creek

Battle Creek, Michigan, 49017, United States
Bronson Methodist Hospital

Kalamazoo, Michigan, 49007, United States
Brooke Army Medical Center

Fort Sam Houston, Texas, 78234, United States
Cancer Care Northwest - Spokane South

Spokane, Washington, 99202, United States
Cancer Center of Kansas - Chanute

Chanute, Kansas, 66720, United States
Cancer Center of Kansas - Dodge City

Dodge City, Kansas, 67801, United States
Cancer Center of Kansas - El Dorado

El Dorado, Kansas, 67042, United States
Cancer Center of Kansas - Newton

Newton, Kansas, 67114, United States
Cancer Center of Kansas - Ottawa

Ottawa, Kansas, 66067, United States
Cancer Center of Kansas - Parsons

Parsons, Kansas, 67357, United States
Cancer Center of Kansas - Pratt

Pratt, Kansas, 67124, United States
Cancer Center of Kansas - Salina

Salina, Kansas, 67401, United States
Cancer Center of Kansas - Wellington

Wellington, Kansas, 67152, United States
Cancer Center of Kansas - Wichita

Wichita, Kansas, 67214, United States
Cancer Center of Kansas - Winfield

Winfield, Kansas, 67156, United States
Cancer Center of Kansas-Independence

Independence, Kansas, 67301, United States
Cancer Center of Kansas-Kingman

Kingman, Kansas, 67068, United States
Cancer Center of Kansas-Wichita Medical Arts Tower

Wichita, Kansas, 67208, United States
Cancer Research Consortium of West Michigan NCORP

Grand Rapids, Michigan, 49503, United States
CancerCare Manitoba

Winnipeg, Manitoba, R3E 0V9, Canada
Carle BroMenn Medical Center

Normal, Illinois, 61761, United States
Carle Cancer Center

Urbana, Illinois, 61801, United States
Carle Cancer Institute Normal

Normal, Illinois, 61761, United States
Carolinas Medical Center/Levine Cancer Institute

Charlotte, North Carolina, 28203, United States
Centerpoint Medical Center LLC

Independence, Missouri, 64057, United States
Central Washington Hospital

Wenatchee, Washington, 98801, United States
Christiana Care - Union Hospital

Elkton, Maryland, 21921, United States
Christiana Care Health System-Christiana Hospital

Newark, Delaware, 19718, United States
City of Hope Comprehensive Cancer Center

Duarte, California, 91010, United States
Columbus NCI Community Oncology Research Program

Columbus, Ohio, 43215, United States
Community Medical Center

Missoula, Montana, 59804, United States
Cooper Hospital University Medical Center

Camden, New Jersey, 08103, United States
Corewell Health Dearborn Hospital

Dearborn, Michigan, 48124, United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital

Grand Rapids, Michigan, 49503, United States
Cotton O'Neil Cancer Center / Stormont Vail Health

Topeka, Kansas, 66606, United States
Cross Cancer Institute

Edmonton, Alberta, T6G 1Z2, Canada
Dana-Farber Cancer Institute

Boston, Massachusetts, 02215, United States
Dayton NCI Community Oncology Research Program

Dayton, Ohio, 45459, United States
Dayton Veterans Affairs Medical Center

Dayton, Ohio, 45428, United States
Deaconess Medical Center

Billings, Montana, 59107, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Deerpath Medical Associates

Lake Forest, Illinois, 60045, United States
Doctor H. Bliss Murphy Cancer Centre

St. John's, Newfoundland and Labrador, A1B 3V6, Canada
Doctors Hospital

Columbus, Ohio, 43228, United States
DuPage Medical Group-Ogden

Naperville, Illinois, 60563, United States
Duly Health and Care Joliet

Joliet, Illinois, 60435, United States
ECU Health Oncology Kinston

Kinston, North Carolina, 28501, United States
Eastern Maine Medical Center

Bangor, Maine, 04401, United States
Eastern Montana Cancer Center

Miles City, Montana, 59301, United States
Edward H Kaplan MD and Associates

Skokie, Illinois, 60076, United States
Eureka Hospital

Eureka, Illinois, 61530, United States
Fairfield Medical Center

Lancaster, Ohio, 43130, United States
Fairview Cancer Center - Woodbury

Woodbury, Minnesota, 55125, United States
Fairview Ridges Hospital

Burnsville, Minnesota, 55337, United States
Fairview Southdale Hospital

Edina, Minnesota, 55435, United States
Fort Wayne Medical Oncology and Hematology Inc-Parkview

Fort Wayne, Indiana, 46845, United States
Franciscan Saint Anthony Health-Michigan City

Michigan City, Indiana, 46360, United States
Franciscan Saint Francis Health-Beech Grove

Beech Grove, Indiana, 46107, United States
Fred Hutchinson Cancer Center

Seattle, Washington, 98109, United States
Galesburg Cottage Hospital

Galesburg, Illinois, 61401, United States
Geisinger Medical Center

Danville, Pennsylvania, 17822, United States
Geisinger Medical Group

State College, Pennsylvania, 16801, United States
Geisinger Wyoming Valley/Henry Cancer Center

Wilkes-Barre, Pennsylvania, 18711, United States
Genesis Healthcare System Cancer Care Center

Zanesville, Ohio, 43701, United States
Genesys Regional Medical Center-West Flint Campus

Flint, Michigan, 48532, United States
Glacier Oncology PLLC

Kalispell, Montana, 59901, United States
Glens Falls Hospital

Glens Falls, New York, 12801, United States
Good Samaritan Hospital - Dayton

Dayton, Ohio, 45406, United States
Grady Memorial Hospital

Delaware, Ohio, 43015, United States
Graham Hospital Association

Canton, Illinois, 61520, United States
Grandview Hospital

Dayton, Ohio, 45405, United States
Grant Medical Center

Columbus, Ohio, 43215, United States
Great Falls Clinic

Great Falls, Montana, 59405, United States
Greene Memorial Hospital

Xenia, Ohio, 45385, United States
Guardian Oncology and Center for Wellness

Missoula, Montana, 59804, United States
Gundersen Lutheran Medical Center

La Crosse, Wisconsin, 54601, United States
HSHS Sacred Heart Hospital

Eau Claire, Wisconsin, 54701, United States
Harborview Medical Center

Seattle, Washington, 98104, United States
Heartland Cancer Research NCORP

Decatur, Illinois, 62526, United States
Heartland Regional Medical Center

Saint Joseph, Missouri, 64506, United States
Hematology Oncology Associates of Central New York-East Syracuse

East Syracuse, New York, 13057, United States
Hematology Oncology Associates of Illinois - Skokie

Skokie, Illinois, 60076, United States
Hematology and Oncology Associates

Chicago, Illinois, 60611, United States
Hennepin County Medical Center

Minneapolis, Minnesota, 55415, United States
Henry Ford Health Providence Southfield Hospital

Southfield, Michigan, 48075, United States
Henry Ford Health Saint John Hospital

Detroit, Michigan, 48236, United States
Henry Ford Health Warren Hospital

Warren, Michigan, 48093, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Holland Community Hospital

Holland, Michigan, 49423, United States
Hopedale Medical Complex - Hospital

Hopedale, Illinois, 61747, United States
Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112, United States
Hurley Medical Center

Flint, Michigan, 48503, United States
Hutchinson Area Health Care

Hutchinson, Minnesota, 55350, United States
Illinois Cancer Specialists-Niles

Niles, Illinois, 60714, United States
Illinois CancerCare-Galesburg

Galesburg, Illinois, 61401, United States
Illinois CancerCare-Ottawa Clinic

Ottawa, Illinois, 61350, United States
Illinois CancerCare-Peoria

Peoria, Illinois, 61615, United States
Illinois Valley Hospital

Peru, Illinois, 61354, United States
Interlakes Foundation Inc-Rochester

Rochester, New York, 14623, United States
Intermountain Health Lutheran Hospital

Wheat Ridge, Colorado, 80401, United States
Internal Medicine of Bozeman

Bozeman, Montana, 59715, United States
Iredell Memorial Hospital

Statesville, North Carolina, 28677, United States
Jefferson Torresdale Hospital

Philadelphia, Pennsylvania, 19114, United States
Jesse Brown Veterans Affairs Medical Center

Chicago, Illinois, 60612, United States
Juravinski Cancer Centre at Hamilton Health Sciences

Hamilton, Ontario, L8V 5C2, Canada
Kadlec Clinic Hematology and Oncology

Kennewick, Washington, 99336, United States
Kaiser Permanente Medical Center - Santa Clara

Santa Clara, California, 95051, United States
Kaiser Permanente Northwest

Portland, Oregon, 97227, United States
Kaiser Permanente Sacramento Medical Center

Sacramento, California, 95825, United States
Kaiser Permanente San Leandro

San Leandro, California, 94577, United States
Kaiser Permanente Washington

Seattle, Washington, 98112, United States
Kaiser Permanente-Fremont

Fremont, California, 94538, United States
Kaiser Permanente-Oakland

Oakland, California, 94611, United States
Kaiser Permanente-Redwood City

Redwood City, California, 94063, United States
Kaiser Permanente-Richmond

Richmond, California, 94801, United States
Kaiser Permanente-Roseville

Roseville, California, 95661, United States
Kaiser Permanente-San Francisco

San Francisco, California, 94115, United States
Kaiser Permanente-San Rafael

San Rafael, California, 94903, United States
Kaiser Permanente-Santa Rosa

Santa Rosa, California, 95403, United States
Kaiser Permanente-Santa Teresa-San Jose

San Jose, California, 95119, United States
Kaiser Permanente-South Sacramento

Sacramento, California, 95823, United States
Kaiser Permanente-South San Francisco

South San Francisco, California, 94080, United States
Kaiser Permanente-Stockton

Stockton, California, 95210, United States
Kaiser Permanente-Vallejo

Vallejo, California, 94589, United States
Kaiser Permanente-Walnut Creek

Walnut Creek, California, 94596, United States
Kalispell Medical Oncology

Kalispell, Montana, 59901, United States
Kansas City NCI Community Oncology Research Program

Prairie Village, Kansas, 66208, United States
Kettering Medical Center

Kettering, Ohio, 45429, United States
Kewanee Hospital

Kewanee, Illinois, 61443, United States
Lake Huron Medical Center

Port Huron, Michigan, 48060, United States
Lawrence Memorial Hospital

Lawrence, Kansas, 66044, United States
Lenoir Memorial Hospital

Kinston, North Carolina, 28501, United States
Lewistown Hospital

Lewistown, Pennsylvania, 17044, United States
Liberty Hospital

Liberty, Missouri, 64068, United States
Licking Memorial Hospital

Newark, Ohio, 43055, United States
Logan Health Medical Center

Kalispell, Montana, 59901, United States
London Regional Cancer Program

London, Ontario, N6A 4L6, Canada
Louisiana State University Health Science Center

New Orleans, Louisiana, 70112, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
Marietta Memorial Hospital

Marietta, Ohio, 45750, United States
Marshfield Clinic - Wisconsin Rapids Center

Wisconsin Rapids, Wisconsin, 54494, United States
Marshfield Clinic Cancer Center at Sacred Heart

Eau Claire, Wisconsin, 54701, United States
Marshfield Clinic-Wausau Center

Wausau, Wisconsin, 54401, United States
Marshfield Medical Center

Marshfield, Wisconsin, 54449, United States
Marshfield Medical Center - Minocqua

Minocqua, Wisconsin, 54548, United States
Marshfield Medical Center - Weston

Weston, Wisconsin, 54476, United States
Marshfield Medical Center-Marshfield

Marshfield, Wisconsin, 54449, United States
Marshfield Medical Center-Rice Lake

Rice Lake, Wisconsin, 54868, United States
Mary Bird Perkins Cancer Center

Baton Rouge, Louisiana, 70809, United States
Mary Imogene Bassett Hospital

Cooperstown, New York, 13326, United States
Mary Rutan Hospital

Bellefontaine, Ohio, 43311, United States
Mason District Hospital

Havana, Illinois, 62644, United States
Massachusetts General Hospital Cancer Center

Boston, Massachusetts, 02114, United States
Mayo Clinic in Florida

Jacksonville, Florida, 32224-9980, United States
Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States
McFarland Clinic - Ames

Ames, Iowa, 50010, United States
McLaren Cancer Institute-Northern Michigan

Petoskey, Michigan, 49770, United States
McLeod Regional Medical Center

Florence, South Carolina, 29506, United States
Mcdonough District Hospital

Macomb, Illinois, 61455, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Medical X-Ray Center

Sioux Falls, South Dakota, 57105, United States
Meeker County Memorial Hospital

Litchfield, Minnesota, 55355, United States
Memorial Hospital

Carthage, Illinois, 62321, United States
Memorial Hospital of Arkansas City

Arkansas City, Kansas, 67005, United States
Menorah Medical Center

Overland Park, Kansas, 66209, United States
Mercy Health Partners-Hackley Campus

Muskegon, Michigan, 49442, United States
Mercy Hospital

Coon Rapids, Minnesota, 55433, United States
Mercy Hospital Saint Louis

St Louis, Missouri, 63141, United States
Mercy Hospital and Medical Center

Chicago, Illinois, 60616, United States
Mercy Infusion Center - Chippewa

St Louis, Missouri, 63109, United States
Methodist Medical Center of Illinois

Peoria, Illinois, 61636, United States
Metro Minnesota Community Oncology Research Consortium

Saint Louis Park, Minnesota, 55416, United States
Miami Valley Hospital

Dayton, Ohio, 45409, United States
Miami Valley Hospital North

Dayton, Ohio, 45415, United States
Michigan Cancer Research Consortium NCORP

Ann Arbor, Michigan, 48106, United States
Midwest Cancer Research Group Incorporated

Skokie, Illinois, 60077, United States
Midwest Center for Hematology Oncology

Joliet, Illinois, 60432, United States
Minnesota Oncology Hematology PA-Maplewood

Maplewood, Minnesota, 55109, United States
Minnesota Oncology Hematology PA-Woodbury

Woodbury, Minnesota, 55125, United States
Minor and James Medical PLLC

Seattle, Washington, 98104, United States
Missouri Cancer Associates

Columbia, Missouri, 65201, United States
Moffitt Cancer Center

Tampa, Florida, 33612, United States
Montana Cancer Consortium NCORP

Billings, Montana, 59102, United States
Montana Cancer Specialists

Missoula, Montana, 59802, United States
Montefiore Medical Center-Wakefield Campus

The Bronx, New York, 10466, United States
Montrose Memorial Hospital

Montrose, Colorado, 81401, United States
Mount Carmel Health Center West

Columbus, Ohio, 43222, United States
Mount Nittany Medical Center

State College, Pennsylvania, 16803, United States
Munson Medical Center

Traverse City, Michigan, 49684, United States
MyMichigan Medical Center Saginaw

Saginaw, Michigan, 48601, United States
North Kansas City Hospital

Kansas City, Missouri, 64116, United States
North Memorial Medical Health Center

Robbinsdale, Minnesota, 55422, United States
Northern Rockies Radiation Oncology Center

Billings, Montana, 59101, United States
Northwestern University

Chicago, Illinois, 60611, United States
OSF Saint Anthony's Health Center

Alton, Illinois, 62002, United States
OSF Saint Francis Medical Center

Peoria, Illinois, 61637, United States
OSF Saint Francis Radiation Oncology at Pekin

Pekin, Illinois, 61554, United States
OSF Saint Joseph Medical Center

Bloomington, Illinois, 61701, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
OhioHealth Mansfield Hospital

Mansfield, Ohio, 44903, United States
Oregon Health and Science University

Portland, Oregon, 97239, United States
Orlando Health Cancer Institute

Orlando, Florida, 32806, United States
Ottawa Regional Hospital and Healthcare Center

Ottawa, Illinois, 61350, United States
Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416, United States
PeaceHealth Saint Joseph Medical Center

Bellingham, Washington, 98225, United States
PeaceHealth Southwest Medical Center

Vancouver, Washington, 98664, United States
PeaceHealth United General Medical Center

Sedro-Woolley, Washington, 98284, United States
Pekin Hospital

Pekin, Illinois, 61554, United States
Penn State Milton S Hershey Medical Center

Hershey, Pennsylvania, 17033-0850, United States
Perry Memorial Hospital

Princeton, Illinois, 61356, United States
Poudre Valley Hospital

Fort Collins, Colorado, 80524, United States
Proctor Hospital

Peoria, Illinois, 61614, United States
Providence Medical Center

Kansas City, Kansas, 66112, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center

Burbank, California, 91505, United States
QEII Health Sciences Centre/Nova Scotia Health Authority

Halifax, Nova Scotia, B3H 2Y9, Canada
Radiation Oncology Practice Corporation - North

Kansas City, Missouri, 64154, United States
Radiation Oncology Practice Corporation South

Kansas City, Missouri, 64114, United States
Radiation Oncology Practice Corporation Southwest

Overland Park, Kansas, 66210, United States
Regions Hospital

Saint Paul, Minnesota, 55101, United States
Reid Health

Richmond, Indiana, 47374, United States
Research Medical Center

Kansas City, Missouri, 64132, United States
Ridgeview Medical Center

Waconia, Minnesota, 55387, United States
Riverside Methodist Hospital

Columbus, Ohio, 43214, United States
Riverview Medical Center/Booker Cancer Center

Red Bank, New Jersey, 07701, United States
Rocky Mountain Regional VA Medical Center

Aurora, Colorado, 80045, United States
Rush-Copley Medical Center

Aurora, Illinois, 60504, United States
Rutherford Hospital

Rutherfordton, North Carolina, 28139, United States
SSM Health Good Samaritan

Mount Vernon, Illinois, 62864, United States
SSM Health Saint Louis University Hospital

St Louis, Missouri, 63104, United States
Saint Ann's Hospital

Westerville, Ohio, 43081, United States
Saint Francis Children's Hospital

Tulsa, Oklahoma, 74136, United States
Saint Francis Hospital - Wilmington

Wilmington, Delaware, 19805, United States
Saint Francis Medical Center

Cape Girardeau, Missouri, 63703, United States
Saint Francis Regional Medical Center

Shakopee, Minnesota, 55379, United States
Saint James Community Hospital and Cancer Treatment Center

Butte, Montana, 59701, United States
Saint John's Hospital - Healtheast

Maplewood, Minnesota, 55109, United States
Saint Joseph Health Center

Kansas City, Missouri, 64114, United States
Saint Joseph Medical Center Hematology and Oncology - Silverdale

Silverdale, Washington, 98383, United States
Saint Joseph's Hospital - Healtheast

Saint Paul, Minnesota, 55102, United States
Saint Louis-Cape Girardeau CCOP

St Louis, Missouri, 63141, United States
Saint Luke's Hospital of Kansas City

Kansas City, Missouri, 64111, United States
Saint Luke's University Hospital-Bethlehem Campus

Bethlehem, Pennsylvania, 18015, United States
Saint Margaret's Hospital

Spring Valley, Illinois, 61362, United States
Saint Patrick Hospital - Community Hospital

Missoula, Montana, 59802, United States
Saint Peter's Community Hospital

Helena, Montana, 59601, United States
Saint Rita's Medical Center

Lima, Ohio, 45801, United States
Saint Vincent Frontier Cancer Center

Billings, Montana, 59102, United States
Saint Vincent Healthcare

Billings, Montana, 59101, United States
Salina Regional Health Center

Salina, Kansas, 67401, United States
Sanford Cancer Center Oncology Clinic

Sioux Falls, South Dakota, 57104, United States
Sanford USD Medical Center - Sioux Falls

Sioux Falls, South Dakota, 57117-5134, United States
Saskatoon Cancer Centre

Saskatoon, Saskatchewan, S7N 4H4, Canada
Singing River Hospital

Pascagoula, Mississippi, 39581, United States
Skagit Valley Hospital

Mount Vernon, Washington, 98274, United States
Southeast Clinical Oncology Research Consortium NCORP

Winston-Salem, North Carolina, 27104, United States
Southeast Missouri Hospital

Cape Girardeau, Missouri, 63701, United States
Southwest Medical Center

Liberal, Kansas, 67901, United States
Spartanburg Medical Center

Spartanburg, South Carolina, 29303, United States
Spectrum Health Big Rapids Hospital

Big Rapids, Michigan, 49307, United States
Springfield Memorial Hospital

Springfield, Illinois, 62781, United States
Springfield Regional Medical Center

Springfield, Ohio, 45504, United States
State University of New York Upstate Medical University

Syracuse, New York, 13210, United States
Stony Brook University Medical Center

Stony Brook, New York, 11794, United States
Swedish American Hospital

Rockford, Illinois, 61104, United States
Swedish Covenant Hospital

Chicago, Illinois, 60625, United States
Swedish Medical Center-First Hill

Seattle, Washington, 98122, United States
Syracuse Veterans Administration Medical Center

Syracuse, New York, 13210, United States
The Moncton Hospital

Moncton, New Brunswick, E1C 6Z8, Canada
Tod Children's Hospital - Forum Health

Youngstown, Ohio, 44501, United States
Trinity Health Grand Rapids Hospital

Grand Rapids, Michigan, 49503, United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor

Ann Arbor, Michigan, 48106, United States
Trinity Health Saint Joseph Mercy Oakland Hospital

Pontiac, Michigan, 48341, United States
Trinity Health Saint Mary Mercy Livonia Hospital

Livonia, Michigan, 48154, United States
UCHealth University of Colorado Hospital

Aurora, Colorado, 80045, United States
USC / Norris Comprehensive Cancer Center

Los Angeles, California, 90033, United States
United Hospital

Saint Paul, Minnesota, 55102, United States
Unity Hospital

Fridley, Minnesota, 55432, United States
University Health Network-Princess Margaret Hospital

Toronto, Ontario, M5G 2M9, Canada
University Health Truman Medical Center

Kansas City, Missouri, 64108, United States
University Hospital

San Antonio, Texas, 78229, United States
University Medical Center New Orleans

New Orleans, Louisiana, 70112, United States
University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637, United States
University of Cincinnati Cancer Center-UC Medical Center

Cincinnati, Ohio, 45219, United States
University of Illinois

Chicago, Illinois, 60612, United States
University of Kansas Health System Saint Francis Campus

Topeka, Kansas, 66606, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center

Miami, Florida, 33136, United States
University of Michigan Health - Sparrow Lansing

Lansing, Michigan, 48912, United States
University of Michigan Health - West

Wyoming, Michigan, 49519, United States
University of Michigan Rogel Cancer Center

Ann Arbor, Michigan, 48109, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87106, United States
University of Rochester

Rochester, New York, 14642, United States
University of Texas Health Science Center at San Antonio

San Antonio, Texas, 78229, United States
University of Washington Medical Center - Montlake

Seattle, Washington, 98195, United States
Unspecified Site

Rockville, Maryland, 20852, United States
Upper Valley Medical Center

Troy, Ohio, 45373, United States
Valley Radiation Oncology

Peru, Illinois, 61354, United States
Verdun Hospital Centre

Montreal, Quebec, H4G 2A3, Canada
Virginia Piper Cancer Institute

Minneapolis, Minnesota, 55407, United States
Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157, United States
Wayne Memorial Hospital

Goldsboro, North Carolina, 27534, United States
Wayne Radiation Oncology

Goldsboro, North Carolina, 27534, United States
Welch Cancer Center

Sheridan, Wyoming, 82801, United States
Wenatchee Valley Hospital and Clinics

Wenatchee, Washington, 98801, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007, United States
West Penn Hospital

Pittsburgh, Pennsylvania, 15224, United States
West Virginia University Healthcare

Morgantown, West Virginia, 26506, United States
Western Illinois Cancer Treatment Center

Galesburg, Illinois, 61401, United States
Wichita NCI Community Oncology Research Program

Wichita, Kansas, 67214, United States
Wilford Hall Medical Center

Lackland Air Force Base, Texas, 78236, United States
Wilson Medical Center

Wilson, North Carolina, 27893, United States
Wright-Patterson Medical Center

Wright-Patterson Air Force Base, Ohio, 45433, United States
York Hospital

York Village, Maine, 03909, United States

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