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Stronger chemo combo tested to stop colon cancer return in High-Risk patients

NCT ID NCT02967289

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 30 times

Summary

This study tested whether a stronger chemotherapy combination (mFOLFIRINOX) is better than the standard one (mFOLFOX) at preventing cancer from coming back in people with high-risk stage III colon cancer after surgery. About 792 adults aged 18 to 74 took part. The main goal was to see which treatment led to longer time without cancer returning.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Allan Blair Cancer Centre

    Regina, Saskatchewan, Canada

  • CHD de Vendée

    La Roche-sur-Yon, France

  • CHP Saint Grégoire

    Saint-Grégoire, France

  • Centre Hospitalier Annecy Genevois

    Pringy, France

  • Centre hospitalier de l'Université de Montréal

    Montreal, Quebec, Canada

  • Ch Emile Roux

    Le Puy-en-Velay, France

  • Clinique de la Côte d'Emeraude

    St-Malo, France

  • Hopital Charles LeMoyne

    Greenfield Park, Quebec, Canada

  • Hospices civils de Lyon - Hôpital Edouard Herriot

    Lyon, France

  • Hôpital Européen Georges Pompidou

    Paris, France

  • Hôpital Saint Antoine

    Paris, France

  • Hôpital privé Jean Mermoz

    Lyon, France

  • Icm Val D'Aurelle

    Montpellier, France

  • Institut Jean Godinot

    Reims, France

  • Institut de Cancérologie de l'Ouest -site Paul Papin

    Angers, France

  • Institut de Cancérologie de l'Ouest -site René Gauducheau

    Nantes, France

  • The PEI Cancer Treatment Centre Queen Elizabeth Hospital

    Charlottetown, Prince Edward Island, Canada

Conditions

Explore the condition pages connected to this study.