Lung cancer biopsy showdown: does a lab tech at your side improve genetic testing?

NCT ID NCT04945317

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jan 04, 2026 · Last updated May 21, 2026 · Updated 20 times

Summary

This study compares two ways of taking tissue samples from lung cancer patients to see which method provides better samples for genetic testing. About 349 adults with known or suspected non-small cell lung cancer will be randomly assigned to have a biopsy with or without a cytotechnologist providing real-time feedback on sample quality. The goal is to improve the success rate of genetic testing, which helps doctors choose the most effective treatments.

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Contacts and locations

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Locations

Johns Hopkins Bayview Medical Center

Baltimore, Maryland, 21224, United States
Johns Hopkins Hospital

Baltimore, Maryland, 21287, United States
Northwestern Medicine

Chicago, Illinois, 60611, United States
The Medical University of South Carolina (MUSC)

Charleston, South Carolina, 29425, United States

Conditions

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NON SMALL CELL LUNG CANCER NSCLC NON-SMALL CELL LUNG CANCER (NSCLC)