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New anesthesia approach may speed recovery in lung cancer surgery

NCT ID NCT07327736

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of anesthesia for early-stage lung cancer surgery: one that lets patients breathe on their own and one that uses a breathing tube. Researchers want to see which method leads to a shorter hospital stay and less pain medication use. The study will include 410 adults with small lung tumors (3 cm or less) and aims to find a safer, more effective way to perform surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 410 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Dec 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Up to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≤ 75 years; * Gender is not limited; * Patients with suspected T1 stage non-small cell lung cancer (NSCLC) in preoperative clinical staging, with thin-slice CT showing that the maximum tumor diameter is ≤ 3.0 cm, single or multiple nodules, and the nodules requiring surgical resection are located in the same ipsilateral lung lobe, with the number of nodules resected simultaneously ≤ 3; * American Society of Anesthesiologists (ASA) classification ≤ Grade III (preferably Grade I - II is recommended); * Eastern Cooperative Oncology Group (ECOG) performance status 0 - 1; * Body Mass Index (BMI) \< 25 kg·m-²; * Normal cardiopulmonary function: predicted forced expiratory volume in the first second (FEV1%) \> 50%, resting blood gas analysis showing arterial oxygen partial pressure (PaO2) ≥ 75 mmHg, arterial carbon dioxide partial pressure (PaCO2) \< 45 mmHg; ejection fraction (EF) \> 50%, 6-minute walk distance (6MWD) ≥ 350 m; * No severe upper airway lesions, Mallampati classification I - II; * No contraindications related to paravertebral nerve block and intercostal nerve block; * Estimated surgical time ≤ 150 minutes; * Patients have no history of clinically significant cardiac or neurological problems. Exclusion Criteria: * A history of ipsilateral lung surgery; * Interstitial pneumonia, pulmonary fibrosis, severe emphysema, severe chronic obstructive pulmonary disease, acute phase of pulmonary infection, or uncontrolled asthma; * Sleep apnea syndrome with anticipated airway difficulty or difficulty in airway management; * Preoperative complications including coagulation dysfunction, hypoxemia, hypercapnia, or hepatic/renal insufficiency; * Alteration of anesthesia or surgical plan; * Persistent cough or increased risk of high airway secretion reflux; * Mental disorders, inability to communicate, or refusal to sign the informed consent form; * Participation in other clinical trials within 1 month before this trial; * Those who are deemed unfit to participate in this trial by the researchers.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The official record

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