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New anesthesia combo may reduce risks during chest surgery

NCT ID NCT07347496

Symptom relief Sponsor: The First Affiliated Hospital of Xinxiang Medical College Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a newer anesthesia drug, remimazolam, with the standard drug propofol (both combined with a painkiller) for people having chest surgery. The goal is to see if remimazolam causes fewer problems like low oxygen levels or low blood pressure during the operation. About 50 adults aged 18-75 will take part, and their safety and recovery will be closely monitored.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

May 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients scheduled for elective thoracic surgery (e.g., pulmonary lobectomy, esophagectomy) under general anesthesia with preserved spontaneous respiration. * American Society of Anesthesiologists (ASA) physical status class I-III. * Age between 18 and 75 years. * Provide written informed consent. Exclusion Criteria: * Severe hepatic or renal dysfunction (e.g., Child-Pugh class C, eGFR \< 30 mL/min/1.73m²). * Severe respiratory dysfunction (e.g., COPD GOLD stage 3-4, severe asthma). * Anticipated difficult airway (e.g., Mallampati class IV, history of difficult intubation). * Known allergy or hypersensitivity to benzodiazepines, opioids, or propofol. * Pregnancy or lactation. * Participation in another interventional clinical trial within the past 3 months. * Mental illness or inability to cooperate with assessments.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthesia Non-intubated anesthesia Thoracic surgery

How to take part

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  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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