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Which dental injection hurts least? new study pits 5 devices Head-to-Head

NCT ID NCT07184879

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 38 times

Summary

This study tested five different devices for numbing the roof of the mouth before a tooth extraction. Two hundred healthy adults received the same anesthetic but through different tools, including a standard syringe, a spring-loaded syringe, and a needle-free jet injector. Researchers measured pain, fear, and heart rate to find which method is most comfortable for patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Istanbul Aydın University Faculty of Dentistry, Department of Oral and Maxillofacial Surgery

    Istanbul, Turkey (Türkiye)

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

articaine 4% with epinephrine 1:100,000

What this could lead to

If successful, this could identify a dental injection method that causes less pain and anxiety for patients.

What could go wrong

This is a small, completed study comparing devices, not testing a new drug or cure. Results may not apply to all dental procedures or patients.

Conditions

The condition(s) this trial relates to.

Pain tooth disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.