Can Blood-Type-Matched platelets make transfusions safer?
NCT ID NCT06613425
First seen Sep 11, 2026 · Last updated Sep 11, 2026
Summary
Researchers are testing a new way to prepare platelets for transfusion that matches a patient's ABO blood type. The study enrolls adults aged 18 to 65 who need platelet transfusions for blood disorders. Doctors measure platelet counts and bleeding before and after transfusion to see if the combined platelets work as well as standard platelets, and they track any side effects.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- combined platelets, a blood product made to match ABO blood type
- What this could lead to
- If it works, hospitals could have an easier way to give platelet transfusions that match a patient's blood type, which may lower the chance of reactions and make transfusions more reliable.
- What could go wrong
- This is a single-arm study, meaning everyone receives the same treatment and there is no comparison group, so it cannot prove the approach is better than standard care. Platelet transfusions carry risks of allergic reactions, fever, and other complications, and the results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
-
266 people
The number who actually took part.
- Started
-
Aug 2024
- Finished
-
Mar 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 1\. Aged 18-65 years; 2. Disease treatment in the research hospital; 3. Applied for platelet transfusion therapy. Exclusion Criteria: * 1\. One month before the start of this study, he participated in other clinical trials of drugs and instruments related to platelet transfusion efficacy; 2. Without platelet transfusion indications; 3. Only received platelet transfusion in the outpatient department and left the hospital without efficacy evaluation after transfusion; 4. Gave up platelet transfusion therapy for any reason after enrollment; 5. Transferred or discharged from hospital for any reason before platelet transfusion after enrollment; 6. Did not receive combined platelet transfusion during the 6-month treatment period after enrollment
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Hematologic diseases are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Li Zhang
Chengdu, Sichuan, 610083, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Virtual reality could replace painkillers for bone marrow tests
- Could muscle loss predict blood cancer outcomes?
- Double-Pronged immune cells take aim at stubborn blood cancers
- Could virtual reality help patients recover faster from cell therapy?
- Gentle touch may soothe anxiety for isolated blood cancer patients
- Card game aims to ease tough End-of-Life talks for cancer patients