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New combo therapy shows promise for tough lung cancer

NCT ID NCT05017025

First seen Nov 19, 2025 · Last updated Jun 10, 2026 · Updated 30 times

Summary

This study tests a new drug combination for people with a specific type of advanced lung cancer (EGFR-mutant non-small cell lung cancer). The two drugs, LY3295668 and osimertinib, work by blocking enzymes that help cancer cells grow. The goal is to find the safest dose and see if the combination can control the cancer better than standard treatment. About 32 adults with advanced or metastatic disease are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.