New combo therapy targets liver tumors in rare eye cancer
NCT ID NCT04283890
First seen Sep 30, 2025 · Last updated Apr 30, 2026 · Updated 25 times
Summary
This study tests a combination of two immunotherapy drugs (ipilimumab and nivolumab) plus a chemotherapy drug (melphalan) given directly to the liver for people with advanced uveal melanoma that has spread, especially to the liver. The goal is to see if this approach is safe and can control the cancer both in the liver and elsewhere in the body. About 83 adults aged 18-75 who have not had prior systemic treatment are participating.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Leiden University Medical Center
Leiden, South Holland, 2333 ZA, Netherlands
Conditions
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