New hope for advanced cancer? first human trial of COM503 begins
NCT ID NCT06759649
First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 33 times
Summary
This early-phase trial tests a new drug called COM503, alone or with another drug (zimberelimab), in 200 people with advanced solid tumors that have not responded to standard treatments. The main goal is to check safety and find the best dose. This study does not aim to cure cancer but to control the disease and manage symptoms.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 0221502215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hadassah University Medical Center- Ein Kerem
RECRUITINGJerusalem, Israel, 9112001, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
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NEXT Oncology San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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NEXT Oncology Virginia
RECRUITINGFairfax, Virginia, 22031, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Rabin Medical Center
RECRUITINGPetah Tikva, Israel, 4941492, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Rambam Health Care Campus
RECRUITINGHaifa, Israel, 3109601, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
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START
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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START Midwest
RECRUITINGGrand Rapids, Michigan, 49546, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Chaim Sheba Medical Center
RECRUITINGRamat Gan, Israel, 5465601, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The West Clinic, PLCC dba West Cancer Center
RECRUITINGGermantown, Tennessee, 38138, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yale- New Haven Hospital- Yale Cancer Center
RECRUITINGNew Haven, Connecticut, 06510, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.