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New study reveals best way to spot dangerous colon growths

NCT ID NCT01521091

Diagnosis Sponsor: Shanghai Jiao Tong University School of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared three methods used during colonoscopy to predict whether colorectal growths are cancerous: narrow band imaging (NBI), indigo carmine staining, and acetic acid staining. Researchers studied 565 patients with at least one lesion 6mm or larger. The goal was to see which method most accurately identifies invasive cancer. Results suggest NBI may be the best first choice.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
narrow band imaging, indigo carmine, and acetic acid staining
What this could lead to
If successful, this could help doctors choose the best method to accurately diagnose colorectal lesions during colonoscopy, potentially reducing unnecessary biopsies.
What could go wrong
This is a completed diagnostic accuracy study, not a treatment trial. Results may not apply to all patients or settings, and the methods require specialized equipment and training.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

565 people

The number who actually took part.

Start date

Jan 2009

Finished

Dec 2010

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

consecutive adult patients undergoing colonoscopy and find out more than one lesion ≧ 6mm from Jan 2009 to Dec 2010.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Consecutive patients with more than one lesion ≧ 6mm . Exclusion Criteria: * Patients with chronic inflammatory bowel disease, advanced cancer, insufficient bowel preparation, familial adenomatous polyposis (FAP) * Lesions ≦ 5mm and submucosal tumor (SMT).

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Conditions

The condition(s) this trial relates to.

colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal neoplasms

Contacts and locations

Locations

  • Departments of Gastroenterology and Clinical Laboratory, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine

    Shanghai, 200001, China

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