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50,000 cancer patients join landmark study to unlock better treatments

NCT ID NCT02070146

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 50,000 people with colorectal, small bowel, or anal cancer to learn why some respond better to treatment than others. Researchers will collect data on genetics, lifestyle, and side effects to improve care for all patients, not just those in clinical trials. Participants can also join other studies at the same time.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better predict outcomes and tailor treatments for colorectal cancer patients in everyday practice.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test new therapies. Results may take years and might not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2013

Expected to finish

Jan 2051

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All patients diagnosed with colorectal, small bowel and anal cancer, who are recently diagnosed, have a strong suspicion without pathological confirmation or are currently under treatment or follow up in one of the participating hospitals will be asked to participate in this cohort study.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years * Histological proof of colorectal, small bowel and anal cancer, or a strong suspicion after imaging. * Informed consent for longitudinal observational data collection. Exclusion Criteria: * Mentally incompetent patients. Participation of patients to the PLCRC project does not exclude participation in any other ongoing or future study.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Anal cancer are added.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    70 sites. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Admiraal De Ruyter Ziekenhuis

    RECRUITING

    Goes, Netherlands

  • Albert Schweitzer Ziekenhuis

    RECRUITING

    Dordrecht, Netherlands

  • Alrijne

    RECRUITING

    Leiden, Netherlands

  • Amphia ziekenhuis

    RECRUITING

    Breda, Netherlands

  • Anna Ziekenhuis

    RECRUITING

    Geldrop, Netherlands

    Contact Email: •••••@•••••

  • Antoni van Leeuwenhoek

    RECRUITING

    Amsterdam, Netherlands

  • Antonius Ziekenhuis

    RECRUITING

    Sneek, Netherlands

  • Bernhoven

    RECRUITING

    Oss, Netherlands

  • Bravis ziekenhuis

    RECRUITING

    Roosendaal, Netherlands

  • Canisius Wilhelmina Ziekenhuis

    RECRUITING

    Nijmegen, Netherlands

  • Catharina Ziekenhuis

    RECRUITING

    Eindhoven, Netherlands

  • Deventer Ziekenhuizen

    RECRUITING

    Deventer, Netherlands

  • Diakonessenhuis

    RECRUITING

    Utrecht, Netherlands

  • Dijklander Ziekenhuis

    RECRUITING

    Hoorn, Netherlands

  • Elisabeth-TweeSteden Ziekenhuis

    RECRUITING

    Tilburg, Netherlands

  • Elkerliek Ziekenhuis

    RECRUITING

    Helmond, Netherlands

  • Erasmus MC

    RECRUITING

    Rotterdam, Netherlands

  • Flevoziekenhuis

    RECRUITING

    Almere Stad, Netherlands

  • Franciscus Gasthuis & Vlietland

    RECRUITING

    Rotterdam, Netherlands

  • Frisius MC Heerenveen

    RECRUITING

    Heerenveen, Netherlands

  • Frisius MC Leeuwarden

    RECRUITING

    Leeuwarden, Netherlands

  • Gelre Ziekenhuizen

    RECRUITING

    Apeldoorn, Netherlands

  • Groene Hart Ziekenhuis

    RECRUITING

    Gouda, Netherlands

  • Haaglanden MC

    RECRUITING

    The Hague, Netherlands

  • HagaZiekenhuis

    RECRUITING

    The Hague, Netherlands

  • IJsselland Ziekenhuis

    RECRUITING

    Capelle aan den IJssel, Netherlands

  • Ikazia Ziekenhuis

    RECRUITING

    Rotterdam, Netherlands

  • Isala

    RECRUITING

    Zwolle, Netherlands

  • Jeroen Bosch Ziekenhuis

    RECRUITING

    's-Hertogenbosch, Netherlands

  • Laurentius Ziekenhuis

    RECRUITING

    Roermond, Netherlands

  • Leids Universitair Medisch Centrum

    RECRUITING

    Leiden, Netherlands

  • MAASTRO

    RECRUITING

    Maastricht, Netherlands

  • Maasstad Ziekenhuis

    RECRUITING

    Rotterdam, Netherlands

  • Maastricht UMC+

    RECRUITING

    Maastricht, Netherlands

  • Maasziekenhuis Pantein

    RECRUITING

    Beugen, Netherlands

  • Martini Ziekenhuis

    RECRUITING

    Groningen, Netherlands

  • Maxima Medisch Centrum

    RECRUITING

    Eindhoven, Netherlands

  • Meander Medisch Centrum

    RECRUITING

    Amersfoort, Netherlands

  • Medisch Spectrum Twente

    RECRUITING

    Enschede, Netherlands

  • Noordwest Ziekenhuisgroep

    RECRUITING

    Alkmaar, Netherlands

  • OLVG

    RECRUITING

    Amsterdam, Netherlands

  • Ommelander Ziekenhuis

    RECRUITING

    Groningen, Netherlands

  • Radboud UMC

    RECRUITING

    Nijmegen, Netherlands

  • Reinier de Graaf

    RECRUITING

    Delft, Netherlands

  • Rijnstate

    RECRUITING

    Arnhem, Netherlands

  • Rivas Beaterix Ziekenhuis

    RECRUITING

    Gorinchem, Netherlands

  • Rode Kruis Ziekenhuis

    RECRUITING

    Beverwijk, Netherlands

  • Saxenburgh Groep

    RECRUITING

    Hardenberg, Netherlands

  • Slingeland Ziekenhuis

    RECRUITING

    Doetinchem, Netherlands

  • Spaarne Gasthuis

    RECRUITING

    Haarlem, Netherlands

  • St. Antonius ziekenhuis

    RECRUITING

    Nieuwegein, Netherlands

  • St. Jans Gasthuis

    RECRUITING

    Weert, Netherlands

  • St.Jansdal

    RECRUITING

    Harderwijk, Netherlands

  • Streekziekenhuis Koningin Beatrix

    RECRUITING

    Winterswijk, Netherlands

  • Tergooi

    RECRUITING

    Hilversum, Netherlands

  • Treant Zorggroep

    RECRUITING

    Hoogeveen, Netherlands

  • UMC Groningen

    RECRUITING

    Groningen, Netherlands

  • UMC Utrecht

    RECRUITING

    Utrecht, Netherlands

  • VUmc

    RECRUITING

    Amsterdam, Netherlands

  • Van Weel-Bethesda Ziekenhuis

    RECRUITING

    Dirksland, Netherlands

  • VieCuri Medisch Centrum

    RECRUITING

    Venlo, Netherlands

  • Wilhelmina Ziekenhuis Assen

    RECRUITING

    Assen, Netherlands

  • Zaans Medisch Centrum

    RECRUITING

    Zaandam, Netherlands

  • Ziekenhuis Amstelland

    RECRUITING

    Amstelveen, Netherlands

  • Ziekenhuis Gelderse Vallei

    RECRUITING

    Ede, Netherlands

  • Ziekenhuis Nij Smellinghe

    RECRUITING

    Drachten, Netherlands

  • Ziekenhuis Rivierenland

    RECRUITING

    Tiel, Netherlands

  • Ziekenhuisgroep Twente

    RECRUITING

    Hengelo, Netherlands

  • ZorgSaam

    RECRUITING

    Terneuzen, Netherlands

  • Zuyderland Medisch Centrum

    RECRUITING

    Sittard, Netherlands

More trials for these conditions

Other studies related to the condition(s) this trial covers.