Gum graft showdown: which collagen seal saves more bone?
NCT ID NCT06029322
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests two different collagen materials used to seal the socket after a tooth is pulled, to see which one better preserves the gum and bone for future dental implants. Eighteen adults needing two tooth extractions will each receive both materials at different sites, and the results will be compared using scans and healing scores. The goal is to find out which seal leads to thicker gum tissue and better bone preservation.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- collagen matrix or collagen membrane
- What this could lead to
- If one material works better, dentists may have a clearer choice for preserving gum and bone after tooth removal, improving future implant success.
- What could go wrong
- This is a very small early study with only 18 patients, so results may not apply to everyone. It compares materials, not a new treatment, so no major breakthrough is expected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 18 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2024
- Expected to finish
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Dec 2025
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * At least 21 years old * Good oral hygiene defined as a full-mouth plaque score ≤ 25% (O'Leary, Drake, \& Naylor, 1972) * Need for ARP after tooth extraction at two sites in the maxilla or mandible with \> 50% buccal bone present following tooth extraction * Signed informed consent Exclusion Criteria: * Any systemic disease * Pregnancy * Smoking (will be specifically asked) * Untreated periodontitis * Untreated caries lesions * Suppuration and/or active infection around the failing tooth * Midfacial recession at the failing tooth
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ghent University Hospital
Ghent, East Flanders, 9000, Belgium