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Collagen boost: a new hope for fragile bones?

NCT ID NCT07347236

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking a daily collagen supplement (PROTÉGEN Plus) for 12 weeks helps older adults aged 60+ recover better from a fragility fracture. Participants will be split into two groups: one gets collagen plus standard care, the other gets standard care alone. Researchers will check nutrition, muscle mass, and bone health over 24 weeks to see if collagen speeds up recovery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 76 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female participants aged 60 years and above. * History of a fragility fracture (e.g., hip, wrist, or vertebral fracture) sustained within the past 12 months. * Registered outpatient at Hospital Sultan Abdul Aziz Shah (HSAAS). * Malaysian citizen. * Able to communicate in Bahasa Malaysia or English. * Able and willing to provide written informed consent. * Cognitive function score \>4 on the Elderly Cognitive Assessment Questionnaire (ECAQ). * Currently undergoing a structured rehabilitation programme. * May be receiving antiresorptive osteoporosis therapy or not receiving any osteoporosis pharmacological treatment at the time of recruitment. Exclusion Criteria: * Cognitive impairment, defined as ECAQ score ≤4 * Metabolic bone diseases other than osteoporosis (e.g., Paget's disease, osteomalacia). * Severe endocrine or metabolic disorders affecting bone metabolism (e.g., primary hyperparathyroidism, Cushing's syndrome, hyperthyroidism, hypogonadism, acromegaly). * Terminal illness or palliative care needs (e.g., advanced cancer, end-stage organ failure, late-stage neurodegenerative diseases). * Known allergy to fish, seafood, or collagen supplements, or diagnosis of phenylketonuria. * Kidney disease, including history of kidney stones or chronic kidney disease stage 4-5 (estimated glomerular filtration rate \<44 mL/min/1.73 m²). * Participation in another interventional study that may interfere with the study protocol. * Use of nutritional supplements during the study period. * Prior use of collagen or amino acid-based supplements within the past 6 months. * Non-ambulatory status prior to the fracture. * Unstable medical conditions (e.g., uncontrolled arrhythmias, recent myocardial infarction, unstable angina, uncontrolled hypertension, pulmonary embolism). * Current use of anabolic osteoporosis therapy. * Alcohol dependence or active alcoholism.

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As listed by the trial registrant

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How to take part

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  2. The official record

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Contacts and locations

Locations

  • Hospital Sultan Abdul Aziz Shah (HSAAS), Universiti Putra Malaysia

    Serdang, Selangor, 43400, Malaysia

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