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Chilly dip, hot discovery: cold water may fire up Fat-Burning brown fat

NCT ID NCT05468151

Knowledge-focused Sponsor: Turku University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether taking weekly cold water baths (18°C) for at least 12 weeks can boost brown fat activity in people with obesity. Brown fat is a type of body fat that burns energy to generate heat. Researchers will use special scans to measure blood flow and fuel use in brown fat. The goal is to understand how cold exposure might help develop new treatments for obesity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 45 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2022

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * BMI\>30kg/m2 (for participants with obesity) * BMI\<25kg/m2 (for lean participants) * Waist circumference \>94 cm for men (for participants with obesity) * Waist circumference \> 80 for women (for participants with obesity) * Glucose ≥7.8 and \<11 mmol/L after OGTT (for participants with obesity) Exclusion Criteria: * Being regularly exposed to cold environments for the last 3 months (e.g. having a job as a ski monitor, fishmonger, woodcutter, etc.; or doing sports/leisure activities outdoors for prolonged periods of time, etc.) * Having gone for winter/ice swimming and bathing more than once every 2 weeks during the last 3 months. * Inability to undergo scanning (e.g., claustrophobia) * Pregnancy * Smoking (or use of nicotine based products) * Hypo/hyperthyroidism * Malignancies * Immune disorders * Viral or bacterial infections * Abnormal cardiovascular status, arrhythmia and/or long QTc in ECG, abnormal cardiac murmur, previous history of cardiovascular disease * Allergy to lidocaine or epinephrine, or other local anaesthetics * Weight change (intentional or not) over the last 6-months \> than 5% of body weight * Any other cardiovascular, pulmonary, orthopaedic, neurologic, psychiatric or other conditions that in the opinion of the local clinician/researcher, would preclude participation and successful completion of the protocol, or that would negatively impact or mitigate participation in and completion of the protocol.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity

Contacts and locations

Locations

  • Turku PET Centre

    Turku, Turku, 20520, Finland

More trials for these conditions

Other studies related to the condition(s) this trial covers.