Could cold plasma zap away stubborn Athlete's foot?
NCT ID NCT07056660
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new device that uses cold plasma (a type of energized gas) to treat moderate-to-severe athlete's foot, a stubborn fungal infection. About 220 adults with confirmed infection will receive either the plasma treatment or a fake one to see if it safely reduces skin lesions and symptoms. The goal is to find a more effective and practical option for people who don't get better with standard creams or pills.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 220 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 18 and 70 years, irrespective of sex. * Clinical diagnosis of interdigital tinea pedis (non-hyperkeratotic type), with or without extension to other areas, of moderate to severe intensity, defined as follows: target lesion(s) will have an erythema score of ≥2 and either a desquamation or pruritus score of ≥2, with a total score ≥4 (using a 0-3 scale for each item). * Positive direct potassium hydroxide (KOH) microscopic examination for dermatophytes. * Women of childbearing potential will agree to use effective contraception throughout the study period. * Written informed consent will be obtained prior to enrollment. Exclusion Criteria: * Severe bacterial infection or other dermatological conditions that may interfere with study assessments. * Serious cardiac, hepatic, or renal diseases, diabetes mellitus, or major psychiatric disorders. * Systemic corticosteroid or immunosuppressant use within the past 3 months. * Systemic antifungal agents within the past 2 months or topical antifungal agents within the past 2 weeks. * Pregnancy or breastfeeding.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The 989th Hospital of Chinese People's Liberation Army Joint Logistic Support Force
RECRUITINGLuoyang, Henan, China
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