Brain training may boost social skills in at-risk teens
NCT ID NCT05131035
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a 10-week cognitive training program called SCORES for teens at high risk for psychosis. The program aims to improve processing speed (how fast the brain handles information) through game-like tasks, group coaching, and rewards. Researchers hope better processing speed will lead to improved social functioning and fewer psychosis symptoms. The study enrolls 54 teens and is currently recruiting.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- cognitive remediation program (SCORES) with group coaching and therapy
- What this could lead to
- If it works, this could point toward a non-drug way to improve thinking and social skills in teens at risk for psychosis, possibly lowering their chance of developing the disorder.
- What could go wrong
- This is an early-stage study with only 54 participants, so results may not apply to everyone. The program is intensive (40 hours) and may not work for all teens.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 54 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2021
- Expected to finish
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May 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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14 to 20 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Meet Clinical High Risk (CHR) criteria on the Structured Interview for Psychosis Risk Syndromes, defined by the presence of at least one attenuated positive symptom at a moderate to severe level * A score representing 0.5 SD below the mean on Animal Naming, Trails A or BACS: Symbol Coding from the MATRICS Consensus Cognitive Battery (MCCB). Exclusion Criteria: * Any DSM 5 Schizophrenia-Spectrum diagnosis * Non-English speaking * Past or current history of a clinically significant central nervous system disorder (e.g., seizure disorder) * Estimated IQ\<70 * Significant head injury * Significant substance abuse * Significant visual or auditory impairment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Northwell Health- The Zucker Hillside Hospital
RECRUITINGGlen Oaks, New York, 11042, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can schools catch teen mental health struggles before they escalate?
- Can a phone app curb cannabis use in early psychosis?
- Can a nasal insulin spray rev up brain energy and sharpen thinking in psychosis?
- Can virtual reality from home sharpen social skills in schizophrenia?
- Brain zaps in fast forward: a new hope for psychosis prevention?