Brain boot camp: virtual classes aim to sharpen minds in epilepsy
NCT ID NCT05954182
First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 3 times
Summary
This study tests whether a 12-week virtual group program led by a neuropsychologist can improve memory, focus, and daily functioning in adults with epilepsy. Participants learn brain-health strategies and practice them for a year. Researchers compare their progress to a group that does not receive the training.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- cognitive intervention (virtual group sessions with a neuropsychologist)
- What this could lead to
- If it works, this approach could offer a drug-free way to sharpen thinking and daily functioning for people with epilepsy.
- What could go wrong
- This is a behavioral study, not a treatment for seizures themselves. Results depend on participants sticking with the program, and benefits may vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 170 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2023
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Potential patients will be identified if they have been, or are scheduled to be seen, either in-person or virtually for a clinical visit within the Cleveland Clinic Epilepsy Center * Adults, aged 18-60 years old, with diagnosed epilepsy * Subjective cognitive difficulties based on patient self-report or objective cognitive deficits as determined by neuropsychological tests * Able to independently provide informed consent * Fluent in English * Reading abilities at or above 8th grade level as determined by the Wide Range Achievement Test- 4th Edition (WRAT-4), Reading subtest * Internet access and the ability to participate in online video streaming * No history of resective or ablative epilepsy surgery * Willing and able to participate in cognitive intervention Exclusion Criteria: * Patients with a current diagnosis of non-epileptic or psychogenic seizures * Any patient that has engaged in any form of cognitive rehabilitation/intervention within the last 6 months * Patients currently enrolled in another interventional study for epilepsy at the time of enrollment * Anticipated or scheduled epilepsy surgery within 6 months * Pending litigation related to the cause of epilepsy unless litigation is related to disability application * Undergoing intensive medical treatment for serious or life-threatening illness (e.g., chemotherapy, etc.) that, in the opinion of the investigator, would impact study participation * Serious psychiatric condition that, in the opinion of the investigator, would interfere with participation, such as schizophrenia, active psychosis, active mania, and current suicidal ideation * Currently pregnant or less than 6 weeks postpartum * Significant hearing and/or vision loss that, in the opinion of the investigator would preclude them from participating in remote cognitive testing and engaging in the cognitive intervention * Participants who require an LAR or lack capacity to consent for themselves
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Reading the Brain's signals to predict who benefits from deep brain stimulation
- Can a Comfort-Focused education program improve life with epilepsy?
- Can video games rewire young brains after injury?
- High-Fat Diet's effect on epilepsy: scientists track brain signals
- Epilepsy drug candidate put to the test in healthy volunteers