Coffee's secret link to lungs? new study investigates
NCT ID NCT07391696
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks for chemicals in urine and blood that show how much coffee a person drinks. Researchers will give 100 Chinese Singaporean adults different amounts of coffee and tea over 11 weeks. They hope to find reliable markers of coffee intake and later use them to study links with respiratory diseases.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Coffee (dietary supplement)
- What this could lead to
- If successful, this could help researchers use coffee biomarkers to study whether coffee consumption affects respiratory disease risk.
- What could go wrong
- This is an early biomarker study, not a treatment trial. It may not find clear links, and results may not apply to other populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2020
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 64 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Regular coffee drinkers aged 21-64 years old, Chinese ethnicity Exclusion Criteria: * Healthy individuals who are regular coffee and/or tea drinkers, aged 21-64 years old of Chinese ethnicity with no severe medical conditions and are physically-abled, can participate in the research. However, you cannot participate in or will be released from this study if the following conditions or situations apply to you: * Ineligible screening survey which will consist of basic demographic information and questions pertaining to inclusion/exclusion criteria such as age, gender, current medications, chronic illness, etc * Dislike drinking coffee and tea * Pregnant or breastfeeding * Certain medications including Zanaflex, Sirasalud, Ketanest S, Spravato and Ephedrine Sulfate (See full list of medication) * Present medical conditions: cancer, cardiometabolic diseases, endocrine diseases, depression, anxiety, caffeine/lactose intolerant, fear of needles and/or blood disorders * Recent history of major surgical operations * Past or current user of oral/systemic hormone treatment or therapies * Taken antibiotics in the last 3 months * Taking nutritional supplements (that contains coffee/tea-related compounds naturally found in other plants) * Not willing to travel to the University for the study * Unable to commit to completing all the sessions in the 10-week intervention study
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Saw Swee Hock School of Public Health, National University of Singapore
Singapore, Singapore, 117549, Singapore
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