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New Clot-Busting technique could reduce Long-Term leg damage

NCT ID NCT06124768

Disease control Sponsor: RenJi Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new approach to remove blood clots from deep leg veins in people with acute deep vein thrombosis (DVT). The standard method accesses the vein behind the knee, while the new method uses veins in the calf or the opposite leg. Researchers want to see if the new approach works just as well and reduces the risk of post-thrombotic syndrome, a condition causing chronic leg pain and swelling. About 210 adults with recent DVT will take part.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Percutaneous mechanical thrombectomy (a procedure to remove blood clots using a catheter-based device)
What this could lead to
If successful, this could establish a safer, more effective way to remove blood clots in the leg, potentially lowering the chance of long-term complications like chronic leg pain and swelling.
What could go wrong
This is a relatively small, early-stage study (210 participants) comparing surgical techniques, so results may not apply to all patients. The procedure itself carries risks like bleeding, vessel damage, or clot fragments traveling to the lungs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 210 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2021

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with acute lower limb deep venous thrombosis (DVT) treated by percutaneous mechanical thrombectomy (PMT). The symptoms of DVT should no more than 14 days.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age between 18-85 years old; 2. Acute DVT occurred no more than 14 days since the onset of disease; 3. DVT treated by percutaneous mechanical thrombectomy 4. Informed consent signed by patients. Exclusion Criteria: 1. Patients who are known to be allergic to heparin, low molecular weight heparin, or contrast agent; 2. Women during pregnancy and lactation; 3. Patients with other diseases that may cause difficulty in the study or significantly shorten the life expectancy of patients (\<6 months); 4. Patients who are unable or unwilling to participate in the study.

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Conditions

The condition(s) this trial relates to.

Postthrombotic Syndrome venous thromboembolism Venous Thrombosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Deep vein thrombosis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Renji Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200127, China

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