Can a laser prep scar tissue for better hair transplants?
NCT ID NCT07751523
First seen Aug 07, 2026 · Last updated Aug 07, 2026
Summary
This trial tests whether using a fractional CO2 laser before hair transplant surgery can improve outcomes for people with permanent hair loss due to scars. The laser is thought to improve blood flow and tissue quality in scarred areas, potentially helping transplanted hair grafts survive better. Participants receive either laser treatment plus platelet-rich plasma (PRP) during surgery, or PRP alone, and are followed for 9 months to compare hair growth and satisfaction.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Preoperative fractional CO2 laser followed by follicular unit extraction hair transplantation with intraoperative platelet-rich plasma (PRP) injection
- What this could lead to
- If successful, this approach could improve hair transplant success in scarred areas, offering better hair restoration for people with permanent hair loss from scars.
- What could go wrong
- This is a small early-stage trial with only 20 participants, so results may not apply broadly. The laser and procedure carry risks like scarring, infection, or poor graft survival.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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20 people
The number who actually took part.
- Started
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May 2024
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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16 to 30 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with stable secondary cicatricial alopecia. Male or female participants. Participants with realistic expectations regarding treatment outcomes. All hair types (silky, curly, or normal hair). Presence of an adequate donor site for follicular unit extraction (FUE). Ability and willingness to provide written informed consent. Exclusion Criteria: * Extremes of age. Chronic systemic diseases, including hepatic or renal disease. Receiving chemotherapy or systemic corticosteroid therapy. Platelet disorders or other blood disorders. Pregnancy or lactation. History of keloid formation. Scar duration less than 1 year. Absence of a suitable donor site for hair transplantation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tanta University Hospitals
Tanta, Egypt
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Other studies related to the condition(s) this trial covers.