Pharmacists may help curb deadly Opioid-Alcohol mix
NCT ID NCT05599672
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested a brief counseling program delivered by pharmacists to help people who take prescription opioids and also drink alcohol. The program combined medication review with motivational interviewing to encourage safer use. Researchers enrolled 112 adults and measured changes in alcohol and opioid use. The goal was to see if the approach is acceptable and practical for a larger future study.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Alcohol-targeted Brief Intervention-Medication Therapy Management (ABI-MTM)
- What this could lead to
- If successful, this program could provide a practical way for pharmacists to help people reduce dangerous mixing of opioids and alcohol.
- What could go wrong
- This is a small, early-stage study testing feasibility and preliminary effects, not a proven treatment. Results may not apply to all populations or settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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112 people
The number who actually took part.
- Started
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May 2023
- Finished
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Aug 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * English speaking * ≥18 years * Not receiving cancer treatment * Current alcohol use * Prescribed an opioid medication Exclusion Criteria: * SA 2 exclusion * Are pregnant * Cannot provide collateral contact information for ≥2 persons * Do not have a reliable land line or mobile phone to be contacted by study staff * Are filling only buprenorphine * Plan to leave the area for an extended period of time in the next 3-months, or * Have experienced a psychotic and/or manic episode in the last 30 days
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Tennessee College of Medicine
Nashville, Tennessee, 38103, United States
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