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New ICU checklist aims to make final moments more comfortable

NCT ID NCT05861323

First seen Feb 01, 2026 · Last updated Jun 20, 2026 · Updated 21 times

Summary

This study tests a simple checklist called CMOT (Comfort Measures Only Time Out) for ICU teams. The goal is to reduce distress in patients when breathing machines are removed at the end of life. Researchers will enroll 184 patients and their care teams across four ICUs to see if the checklist is practical and helpful.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical center

    Boston, Massachusetts, 02215, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Comfort Measures Only Time Out (CMOT) checklist protocol

What this could lead to

If it works, this could provide a simple, structured way for ICU teams to reduce patient distress during end-of-life care.

What could go wrong

This is a small, early feasibility study with no control group. The checklist may not reduce distress in practice, and results may not apply to all ICUs.

Conditions

The condition(s) this trial relates to.

Coma Death Hypoventilation ocular motor apraxia, Cogan type respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.