Massive CMML study aims to unlock secrets of rare blood cancer
NCT ID NCT07512882
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is collecting blood and bone marrow samples from 5,000 adults with chronic myelomonocytic leukemia (CMML) to better understand the disease. Researchers hope to improve diagnosis, predict how the disease will progress, and find new treatment options. Participants provide samples during routine care or other clinical trials, but this study does not offer any direct treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Mar 2040
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Cohort of Patients With Chronic Myelomonocytic Leukemia
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years and over * Blood monocytosis ≥ 0.5 × 10⁹/L and ≥ 10% of total white blood cells or * Confirmed diagnosis of chronic myelomonocytic leukemia * Regardless of stage (chronic or transformed), and whether or not currently being treated * Signed informed consent Exclusion Criteria: * Active, uncontrolled infection (particularly hepatitis B, hepatitis C, HIV) * Refusal informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
24 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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AP-HP Hôpital Avicenne
NOT_YET_RECRUITINGBobigny, 93000, France
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AP-HP Hôpital Bicêtre
NOT_YET_RECRUITINGLe Kremlin-Bicêtre, 94270, France
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AP-HP Hôpital Cochin
NOT_YET_RECRUITINGParis, 75014, France
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AP-HP Hôpital Necker
NOT_YET_RECRUITINGParis, 75015, France
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AP-HP Hôpital Saint-Antoine
NOT_YET_RECRUITINGParis, 75012, France
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AP-HP Hôpital Saint-Louis
NOT_YET_RECRUITINGParis, 75475, France
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CHRU Lille Hôpital Claude Huriez
NOT_YET_RECRUITINGLille, 59037, France
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CHRU Nancy Brabois
NOT_YET_RECRUITINGVandœuvre-lès-Nancy, 54511, France
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CHU Amiens Picardie
NOT_YET_RECRUITINGAmiens, 80054, France
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CHU Angers
NOT_YET_RECRUITINGAngers, 49933, France
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CHU Bordeaux
NOT_YET_RECRUITINGPessac, 33604, France
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CHU Grenoble
NOT_YET_RECRUITINGGrenoble, 38000, France
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CHU Limoges
NOT_YET_RECRUITINGLimoges, 87042, France
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CHU Nantes
NOT_YET_RECRUITINGNantes, 44093, France
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CHU Nice Hôpital l'Archet 1
NOT_YET_RECRUITINGNice, 06202, France
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CHU Poitiers
NOT_YET_RECRUITINGPoitiers, 86000, France
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CHU Toulouse
NOT_YET_RECRUITINGToulouse, 31059, France
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CHU Tours
NOT_YET_RECRUITINGTours, 37044, France
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Centre Henri Becquerel
NOT_YET_RECRUITINGRouen, 76038, France
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Centre Hospitalier Saint-Brieuc Hôpital Yves Le Foll
NOT_YET_RECRUITINGSaint-Brieuc, 22000, France
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Centre Hospitalier Sud Francilien
NOT_YET_RECRUITINGCorbeil-Essonnes, 91106, France
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Groupe Hospitalo-Universitaire Caremeau Institut de Cancérologie du Gard
NOT_YET_RECRUITINGNîmes, 30029, France
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Gustave Roussy
RECRUITINGVillejuif, 94805, France
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Hôpital Privé Antony
NOT_YET_RECRUITINGAntony, 92160, France
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Other studies related to the condition(s) this trial covers.
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