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Massive CMML study aims to unlock secrets of rare blood cancer

NCT ID NCT07512882

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is collecting blood and bone marrow samples from 5,000 adults with chronic myelomonocytic leukemia (CMML) to better understand the disease. Researchers hope to improve diagnosis, predict how the disease will progress, and find new treatment options. Participants provide samples during routine care or other clinical trials, but this study does not offer any direct treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 5,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Mar 2040

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Cohort of Patients With Chronic Myelomonocytic Leukemia

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years and over * Blood monocytosis ≥ 0.5 × 10⁹/L and ≥ 10% of total white blood cells or * Confirmed diagnosis of chronic myelomonocytic leukemia * Regardless of stage (chronic or transformed), and whether or not currently being treated * Signed informed consent Exclusion Criteria: * Active, uncontrolled infection (particularly hepatitis B, hepatitis C, HIV) * Refusal informed consent

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    24 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • AP-HP Hôpital Avicenne

    NOT_YET_RECRUITING

    Bobigny, 93000, France

  • AP-HP Hôpital Bicêtre

    NOT_YET_RECRUITING

    Le Kremlin-Bicêtre, 94270, France

  • AP-HP Hôpital Cochin

    NOT_YET_RECRUITING

    Paris, 75014, France

  • AP-HP Hôpital Necker

    NOT_YET_RECRUITING

    Paris, 75015, France

  • AP-HP Hôpital Saint-Antoine

    NOT_YET_RECRUITING

    Paris, 75012, France

  • AP-HP Hôpital Saint-Louis

    NOT_YET_RECRUITING

    Paris, 75475, France

  • CHRU Lille Hôpital Claude Huriez

    NOT_YET_RECRUITING

    Lille, 59037, France

  • CHRU Nancy Brabois

    NOT_YET_RECRUITING

    Vandœuvre-lès-Nancy, 54511, France

  • CHU Amiens Picardie

    NOT_YET_RECRUITING

    Amiens, 80054, France

  • CHU Angers

    NOT_YET_RECRUITING

    Angers, 49933, France

  • CHU Bordeaux

    NOT_YET_RECRUITING

    Pessac, 33604, France

  • CHU Grenoble

    NOT_YET_RECRUITING

    Grenoble, 38000, France

  • CHU Limoges

    NOT_YET_RECRUITING

    Limoges, 87042, France

  • CHU Nantes

    NOT_YET_RECRUITING

    Nantes, 44093, France

  • CHU Nice Hôpital l'Archet 1

    NOT_YET_RECRUITING

    Nice, 06202, France

  • CHU Poitiers

    NOT_YET_RECRUITING

    Poitiers, 86000, France

  • CHU Toulouse

    NOT_YET_RECRUITING

    Toulouse, 31059, France

  • CHU Tours

    NOT_YET_RECRUITING

    Tours, 37044, France

  • Centre Henri Becquerel

    NOT_YET_RECRUITING

    Rouen, 76038, France

  • Centre Hospitalier Saint-Brieuc Hôpital Yves Le Foll

    NOT_YET_RECRUITING

    Saint-Brieuc, 22000, France

  • Centre Hospitalier Sud Francilien

    NOT_YET_RECRUITING

    Corbeil-Essonnes, 91106, France

  • Groupe Hospitalo-Universitaire Caremeau Institut de Cancérologie du Gard

    NOT_YET_RECRUITING

    Nîmes, 30029, France

  • Gustave Roussy

    RECRUITING

    Villejuif, 94805, France

  • Hôpital Privé Antony

    NOT_YET_RECRUITING

    Antony, 92160, France

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