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New hope for cluster headache sufferers? rimegepant shows promise in early trial

NCT ID NCT05264714

First seen Jan 12, 2026 · Last updated May 23, 2026 · Updated 19 times

Summary

This pilot study tested whether rimegepant, a medication already used for migraines, could help prevent cluster headaches. Twenty adults with recurrent cluster headaches took the drug and researchers tracked how many attacks they had each week and how severe the pain was. The goal was to see if rimegepant could reduce the frequency and intensity of these debilitating headaches.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.