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New drug combo targets head and neck cancer with precision radiation

NCT ID NCT04105543

First seen Nov 01, 2025 · Last updated Jun 10, 2026 · Updated 28 times

Summary

This early-phase study tested an experimental drug, CLR 131, that delivers radiation directly to cancer cells, combined with standard external beam radiation. The goal was to see if this combination is safe and can deliver a high dose of radiation to tumors in people whose head and neck cancer has come back. The study enrolled 12 participants and used imaging to measure how much radiation reached the tumor.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • UW Cancer Center Johnson Creek

    Johnson Creek, Wisconsin, 53038, United States

  • University of Wisconsin Carbone Cancer Center

    Madison, Wisconsin, 53792, United States

Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.