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Stomach acid drug may change how schizophrenia medication works

NCT ID NCT07262736

First seen Dec 08, 2025 · Last updated May 20, 2026 · Updated 19 times

Summary

This study measured how the stomach acid drug pantoprazole changes the amount of clozapine in the blood. Clozapine is a key medication for hard-to-treat schizophrenia, but its levels vary a lot between people. 33 healthy adults took clozapine alone and again after pantoprazole to see if the combination affects drug exposure. The goal is to help doctors dose clozapine more safely when pantoprazole is also prescribed.

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Contacts and locations

Locations

  • Pusat Sejahtera (Kesihatan & Pergigian)

    Pulau Pinang, 11800, Malaysia

Conditions

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