New combo aims to beat standard CLL therapy in older patients
NCT ID NCT07321652
First seen Jun 27, 2026 · Last updated Sep 03, 2026 · Updated 5 times
Summary
This Phase 3 trial compares a fixed-duration combination of zanubrutinib and sonrotoclax against continuous zanubrutinib alone in older patients with untreated chronic lymphocytic leukemia or small lymphocytic lymphoma. The study will enroll 466 participants to see if the combo improves progression-free survival. Sonrotoclax blocks a protein that helps cancer cells survive, while zanubrutinib targets another protein that fuels cancer growth.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- zanubrutinib and sonrotoclax
- What this could lead to
- If successful, this could offer a more effective, time-limited treatment option for older patients with CLL/SLL, potentially improving progression-free survival without lifelong therapy.
- What could go wrong
- This is an early Phase 3 trial, so results are not yet known. Adding sonrotoclax may increase side effects, and the fixed-duration approach might not be as effective as continuous therapy for all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 466 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Sep 2038
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * STEP 0: This bone marrow or peripheral blood submission to Adaptive is mandatory prior to registration/randomization for real-time identification of the clone needed for MRD testing. The bone marrow sample should be from the first aspiration (i.e., first pull). Aspirate needle should be redirected if needed to get first pull bone marrow aspirate. It should be obtained as soon after pre-registration as possible to confirm registration eligibility * STEP 0: Patients must be diagnosed with CLL/SLL according to International Workshop on Chronic Lymphocytic Leukemia (IWCLL) 2018 criteria that includes all of the following: * ≥ 5 x10\^9 /L B lymphocytes (5000/μL) in the peripheral blood (CLL) or a lymph node biopsy demonstrating SLL with the below immunophenotype (SLL) * On morphologic review, the leukemic cells must be small mature lymphocytes * Immunophenotype of CLL cells (performed locally) must reveal a clonal B-cell population, which coexpress the B cell surface markers of CD19 and CD20, as well as the T-cell antigen CD5. Patients with bright surface immunoglobulin expression or lack of CD23 expression in \> 10% of cells must lack t(11;14) translocation by interphase cytogenetics * STEP 0: Patients must meet criteria for treatment as defined by IWCLL 2018 guidelines which includes at least one of the following criteria: * Evidence of marrow failure as manifested by the development or worsening of anemia or thrombocytopenia (not attributable to autoimmune hemolytic anemia or thrombocytopenia), typically hemoglobin (Hb) \< 10 g/dL, platelet count \< 100,000/mm\^3 * Massive (\> 6 cm below the costal margin), progressive or symptomatic splenomegaly * Massive nodes (ie, \> 10 cm in longest diameter) or progressive or symptomatic lymphadenopathy * Autoimmune anemia and/or thrombocytopenia that is poorly responsive to standard therapy * Constitutional symptoms, which include any of the following: * Unintentional weight loss of ≥ 10% within the previous 6 months * Significant fatigue (ie. Eastern Cooperative Oncology Group \[ECOG\] performance status \[PS\] ≥ 2) * Fevers \>100.5 °F or 38.0°C for 2 weeks or more without evidence of infection * Night sweats \> 1 month without evidence of infection * STEP 0: Patients must not have had prior therapy for CLL (except palliative steroids or treatment of autoimmune complications of CLL with rituximab or steroids) * STEP 0: Treatment with rituximab and/or high-dose corticosteroids for autoimmune complications of CLL must be completed prior to enrollment. Palliative steroids must be at a dose not higher than 20 mg/day of prednisone or equivalent corticosteroid at the time of registration * STEP 0: Age ≥ 65 years * STEP 0: ECOG performance status ≤ 2 * STEP 0: Patients with known HIV infection on effective anti-retroviral therapy with undetectable viral load within 6 months prior to registration are eligible for this trial * STEP 0: For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated * STEP 0: Patients with a history of hepatitis C virus (HCV), infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load * STEP 0: Patients must not be receiving active systemic anticoagulation with warfarin. Patients must be off warfarin therapy for at least 5 half-lives washout and with normal INR prior to enrollment * STEP 0: Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients must be class 2B or better. Patients with acute cardiac events within 6 months prior to registration should be carefully evaluated for their suitability for enrollment * STEP 0: No patients with a history of a severe bleeding disorder or a history of hemorrhagic stroke or intracranial hemorrhage * STEP 0: No patients with known active progressive central nervous system (CNS) disease * STEP 0: No known medical condition causing an inability to swallow oral formulations of agents * STEP 1: The adaptive report confirming a measurable and trackable B cell clone * STEP 1: Patients may not have had major surgery within 7 days of enrollment, or minor surgery within 5 days of enrollment. Examples of minor surgery include dental surgery, insertion of a venous access device, skin biopsy, or aspiration of a joint. The decision about whether a surgery is major or minor can be made at the discretion of the treating physician * STEP 1: No patients with ongoing active fungal, bacterial or viral infection requiring systemic therapy except those described in the protocol document * STEP 1: Patients must not require more than 20 mg prednisone or equivalent corticosteroid daily * STEP 1: Patients must not have uncontrolled active systemic infection requiring intravenous antibiotics * STEP 1: Patients must not have continued requirement for therapy with a strong CYP3A4/5 inhibitor or inducer. Any such inhibitor or inducer must have been discontinued at least 14 days or 5 half-lives (whichever is shorter) before the first dose of study drug * STEP 1: Absolute neutrophil count (ANC) ≥ 1,000/mm3 unless due to marrow involvement * STEP 1: Platelet count ≥ 30,000/mm3 * STEP 1: Total bilirubin ≤ 1.5 x upper limit of normal (ULN) (unless due to liver involvement, hemolysis or Gilbert's disease) * STEP 1: Aspartate aminotransferase (AST)(serum glutamic oxaloacetic transaminase \[SGOT\])/ alanine aminotransferase (ALT) (serum glutamic pyruvic transaminase \[SGPT\]) ≤ 3.0 x upper limit of normal (ULN) unless due to disease infiltration of the liver * STEP 1: Calculated (calc.) creatinine clearance by Chronic Kidney Disease Epidemiology Collaboration equation (CKD-EPI) ≥ 30 mL/min * STEP 1: Urine protein to creatinine ratio \< 1 or urine protein ≤ 1+ * STEP 2: Detectable MRD ≥ 10 residual clonal cells per million nucleated cells in peripheral blood at the C15 restaging evaluation from ClonoSEQ * STEP 2: Response of PR, PR-L, CR, CCR or CRi to zanubrutinib sonrotoclax therapy
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Chronic lymphocytic leukemia are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
210 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Locations
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Abbott-Northwestern Hospital
RECRUITINGMinneapolis, Minnesota, 55407, United States
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Ascension Via Christi Hospitals Wichita
RECRUITINGWichita, Kansas, 67214, United States
Contact Email: •••••@•••••
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Avera Cancer Institute
RECRUITINGSioux Falls, South Dakota, 57105, United States
Contact Email: •••••@•••••
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Avera Cancer Institute - Mitchell
RECRUITINGMitchell, South Dakota, 57301, United States
Contact Email: •••••@•••••
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Avera Cancer Institute at Pierre
RECRUITINGPierre, South Dakota, 57501, United States
Contact Email: •••••@•••••
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Avera Cancer Institute at Yankton
RECRUITINGYankton, South Dakota, 57078, United States
Contact Email: •••••@•••••
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Avera Cancer Institute-Aberdeen
RECRUITINGAberdeen, South Dakota, 57401, United States
Contact Email: •••••@•••••
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Baptist Memorial Hospital and Cancer Center-Collierville
RECRUITINGCollierville, Tennessee, 38017, United States
Contact Email: •••••@•••••
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Baptist Memorial Hospital and Cancer Center-Desoto
RECRUITINGSouthhaven, Mississippi, 38671, United States
Contact Email: •••••@•••••
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Baptist Memorial Hospital and Cancer Center-Memphis
RECRUITINGMemphis, Tennessee, 38120, United States
Contact Email: •••••@•••••
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Benefis Sletten Cancer Institute
RECRUITINGGreat Falls, Montana, 59405, United States
Contact Email: •••••@•••••
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Billings Clinic Cancer Center
RECRUITINGBillings, Montana, 59101, United States
Contact Email: •••••@•••••
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Bozeman Health Deaconess Hospital
RECRUITINGBozeman, Montana, 59715, United States
Contact Email: •••••@•••••
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Broadlawns Medical Center
RECRUITINGDes Moines, Iowa, 50314, United States
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Cancer Care Center of O'Fallon
RECRUITINGO'Fallon, Illinois, 62269, United States
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Cancer Care Specialists of Illinois - Decatur
RECRUITINGDecatur, Illinois, 62526, United States
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Cancer Center of Kansas - Chanute
RECRUITINGChanute, Kansas, 66720, United States
Contact Email: •••••@•••••
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Cancer Center of Kansas - Dodge City
RECRUITINGDodge City, Kansas, 67801, United States
Contact Email: •••••@•••••
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Cancer Center of Kansas - El Dorado
RECRUITINGEl Dorado, Kansas, 67042, United States
Contact Email: •••••@•••••
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Cancer Center of Kansas - McPherson
RECRUITINGMcPherson, Kansas, 67460, United States
Contact Email: •••••@•••••
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Cancer Center of Kansas - Newton
RECRUITINGNewton, Kansas, 67114, United States
Contact Email: •••••@•••••
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Cancer Center of Kansas - Parsons
RECRUITINGParsons, Kansas, 67357, United States
Contact Email: •••••@•••••
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Cancer Center of Kansas - Pratt
RECRUITINGPratt, Kansas, 67124, United States
Contact Email: •••••@•••••
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Cancer Center of Kansas - Salina
RECRUITINGSalina, Kansas, 67401, United States
Contact Email: •••••@•••••
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Cancer Center of Kansas - Wellington
RECRUITINGWellington, Kansas, 67152, United States
Contact Email: •••••@•••••
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Cancer Center of Kansas - Wichita
RECRUITINGWichita, Kansas, 67214, United States
Contact Email: •••••@•••••
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Cancer Center of Kansas - Winfield
RECRUITINGWinfield, Kansas, 67156, United States
Contact Email: •••••@•••••
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Cancer Center of Kansas-Independence
RECRUITINGIndependence, Kansas, 67301, United States
Contact Email: •••••@•••••
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Cancer Center of Kansas-Kingman
RECRUITINGKingman, Kansas, 67068, United States
Contact Email: •••••@•••••
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Cancer Center of Kansas-Liberal
RECRUITINGLiberal, Kansas, 67905, United States
Contact Email: •••••@•••••
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Cancer Center of Kansas-Wichita Medical Arts Tower
RECRUITINGWichita, Kansas, 67208, United States
Contact Email: •••••@•••••
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Carle BroMenn Medical Center
RECRUITINGNormal, Illinois, 61761, United States
Contact Email: •••••@•••••
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Carle Cancer Center
RECRUITINGUrbana, Illinois, 61801, United States
Contact Email: •••••@•••••
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Carle Cancer Institute Normal
RECRUITINGNormal, Illinois, 61761, United States
Contact Email: •••••@•••••
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Carle Physician Group-Effingham
RECRUITINGEffingham, Illinois, 62401, United States
Contact Email: •••••@•••••
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Carle Physician Group-Mattoon/Charleston
RECRUITINGMattoon, Illinois, 61938, United States
Contact Email: •••••@•••••
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Carle at The Riverfront
RECRUITINGDanville, Illinois, 61832, United States
Contact Email: •••••@•••••
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Cedars-Sinai Medical Center
RECRUITINGLos Angeles, California, 90048, United States
Contact Email: •••••@•••••
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Columbus Oncology and Hematology Associates
RECRUITINGDublin, Ohio, 43016, United States
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Columbus Oncology and Hematology Associates Inc
RECRUITINGColumbus, Ohio, 43214, United States
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Community Hospital of Anaconda
RECRUITINGAnaconda, Montana, 59711, United States
Contact Email: •••••@•••••
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Community Medical Center
RECRUITINGMissoula, Montana, 59804, United States
Contact Email: •••••@•••••
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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Decatur Memorial Hospital
RECRUITINGDecatur, Illinois, 62526, United States
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Delaware Health Center-Grady Cancer Center
RECRUITINGDelaware, Ohio, 43015, United States
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Doctors Hospital
RECRUITINGColumbus, Ohio, 43228, United States
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Dublin Methodist Hospital
RECRUITINGDublin, Ohio, 43016, United States
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Duke University Medical Center
RECRUITINGDurham, North Carolina, 27710, United States
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Duluth Clinic Ashland
RECRUITINGAshland, Wisconsin, 54806, United States
Contact Email: •••••@•••••
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Essentia Health - Deer River Clinic
RECRUITINGDeer River, Minnesota, 56636, United States
Contact Email: •••••@•••••
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Essentia Health Cancer Center
RECRUITINGDuluth, Minnesota, 55805, United States
Contact Email: •••••@•••••
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Essentia Health Cancer Center-South University Clinic
RECRUITINGFargo, North Dakota, 58103, United States
Contact Email: •••••@•••••
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Essentia Health Hibbing Clinic
RECRUITINGHibbing, Minnesota, 55746, United States
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Essentia Health Saint Joseph's Medical Center
RECRUITINGBrainerd, Minnesota, 56401, United States
Contact Email: •••••@•••••
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Essentia Health Sandstone
RECRUITINGSandstone, Minnesota, 55072, United States
Contact Email: •••••@•••••
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Essentia Health Virginia Clinic
RECRUITINGVirginia, Minnesota, 55792, United States
Contact Email: •••••@•••••
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Grady Memorial Hospital
RECRUITINGDelaware, Ohio, 43015, United States
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Grant Medical Center
RECRUITINGColumbus, Ohio, 43215, United States
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Gundersen Lutheran Medical Center
RECRUITINGLa Crosse, Wisconsin, 54601, United States
Contact Email: •••••@•••••
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HSHS Saint Elizabeth's Hospital
RECRUITINGO'Fallon, Illinois, 62269, United States
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HaysMed
RECRUITINGHays, Kansas, 67601, United States
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Helen F Graham Cancer Center
RECRUITINGNewark, Delaware, 19713, United States
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Hendrick Medical Center
RECRUITINGAbilene, Texas, 79601, United States
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Idaho Urologic Institute-Meridian
RECRUITINGMeridian, Idaho, 83642, United States
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Illinois CancerCare - Washington
RECRUITINGWashington, Illinois, 61571, United States
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Illinois CancerCare-Bloomington
RECRUITINGBloomington, Illinois, 61704, United States
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Illinois CancerCare-Canton
RECRUITINGCanton, Illinois, 61520, United States
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Illinois CancerCare-Carthage
RECRUITINGCarthage, Illinois, 62321, United States
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Illinois CancerCare-Dixon
RECRUITINGDixon, Illinois, 61021, United States
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Illinois CancerCare-Eureka
RECRUITINGEureka, Illinois, 61530, United States
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Illinois CancerCare-Galesburg
RECRUITINGGalesburg, Illinois, 61401, United States
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Illinois CancerCare-Kewanee Clinic
RECRUITINGKewanee, Illinois, 61443, United States
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Illinois CancerCare-Macomb
RECRUITINGMacomb, Illinois, 61455, United States
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Illinois CancerCare-Ottawa Clinic
RECRUITINGOttawa, Illinois, 61350, United States
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Illinois CancerCare-Pekin
RECRUITINGPekin, Illinois, 61554, United States
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Illinois CancerCare-Peoria
RECRUITINGPeoria, Illinois, 61615, United States
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Illinois CancerCare-Peru
RECRUITINGPeru, Illinois, 61354, United States
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Illinois CancerCare-Princeton
RECRUITINGPrinceton, Illinois, 61356, United States
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Iowa Methodist Medical Center
RECRUITINGDes Moines, Iowa, 50309, United States
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Jefferson Cherry Hill Hospital
RECRUITINGCherry Hill, New Jersey, 08002, United States
Contact Email: •••••@•••••
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Jefferson Torresdale Hospital
RECRUITINGPhiladelphia, Pennsylvania, 19114, United States
Contact Email: •••••@•••••
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Jupiter Medical Center
RECRUITINGJupiter, Florida, 33458, United States
Contact Email: •••••@•••••
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Kaiser Permanente - Panorama City
RECRUITINGPanorama City, California, 91402, United States
Contact Email: •••••@•••••
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Kaiser Permanente Los Angeles Medical Center
RECRUITINGLos Angeles, California, 90027, United States
Contact Email: •••••@•••••
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Kaiser Permanente South Bay
RECRUITINGHarbor City, California, 90710, United States
Contact Email: •••••@•••••
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Kaiser Permanente West Los Angeles
RECRUITINGLos Angeles, California, 90034, United States
Contact Email: •••••@•••••
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Kaiser Permanente-Anaheim
RECRUITINGAnaheim, California, 92806, United States
Contact Email: •••••@•••••
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Kaiser Permanente-Baldwin Park
RECRUITINGBaldwin Park, California, 91706, United States
Contact Email: •••••@•••••
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Kaiser Permanente-Bellflower
RECRUITINGBellflower, California, 90706, United States
Contact Email: •••••@•••••
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Kaiser Permanente-Fontana
RECRUITINGFontana, California, 92335, United States
Contact Email: •••••@•••••
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Kaiser Permanente-Irvine
RECRUITINGIrvine, California, 92618, United States
Contact Email: •••••@•••••
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Kaiser Permanente-Ontario
RECRUITINGOntario, California, 91761, United States
Contact Email: •••••@•••••
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Kaiser Permanente-Riverside
RECRUITINGRiverside, California, 92505, United States
Contact Email: •••••@•••••
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Kaiser Permanente-San Diego Zion
RECRUITINGSan Diego, California, 92120, United States
Contact Email: •••••@•••••
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Kaiser Permanente-San Marcos
RECRUITINGSan Marcos, California, 92078, United States
Contact Email: •••••@•••••
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Kaiser Permanente-Woodland Hills
RECRUITINGWoodland Hills, California, 91367, United States
Contact Email: •••••@•••••
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Kootenai Clinic Cancer Services - Post Falls
RECRUITINGPost Falls, Idaho, 83854, United States
Contact Email: •••••@•••••
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Kootenai Clinic Cancer Services - Sandpoint
RECRUITINGSandpoint, Idaho, 83864, United States
Contact Email: •••••@•••••
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Kootenai Health - Coeur d'Alene
RECRUITINGCoeur d'Alene, Idaho, 83814, United States
Contact Email: •••••@•••••
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Lawrence Memorial Hospital
RECRUITINGLawrence, Kansas, 66044, United States
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Logan Health Medical Center
RECRUITINGKalispell, Montana, 59901, United States
Contact Email: •••••@•••••
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MaineHealth Cancer Care and IV Therapy - South Portland
RECRUITINGSouth Portland, Maine, 04106, United States
Contact Email: •••••@•••••
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MaineHealth Maine Medical Center - Portland
RECRUITINGPortland, Maine, 04102, United States
Contact Email: •••••@•••••
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Margaret R Pardee Memorial Hospital
RECRUITINGHendersonville, North Carolina, 28791, United States
Contact Email: •••••@•••••
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Mary Greeley Medical Center
RECRUITINGAmes, Iowa, 50010, United States
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McFarland Clinic - Ames
RECRUITINGAmes, Iowa, 50010, United States
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McFarland Clinic - Marshalltown
RECRUITINGMarshalltown, Iowa, 50158, United States
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McFarland Clinic - Trinity Cancer Center
RECRUITINGFort Dodge, Iowa, 50501, United States
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Medical Oncology Hematology Consultants PA
RECRUITINGNewark, Delaware, 19713, United States
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Memorial Hospital East
RECRUITINGShiloh, Illinois, 62269, United States
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Mercy Hospital
RECRUITINGCedar Rapids, Iowa, 52403, United States
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Mercy Hospital
RECRUITINGCoon Rapids, Minnesota, 55433, United States
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Mercy Medical Center - Des Moines
RECRUITINGDes Moines, Iowa, 50314, United States
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Missouri Baptist Medical Center
RECRUITINGSt Louis, Missouri, 63131, United States
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Missouri Baptist Sullivan Hospital
RECRUITINGSullivan, Missouri, 63080, United States
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Mount Sinai Medical Center
RECRUITINGMiami Beach, Florida, 33140, United States
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
Contact Email: •••••@•••••
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Ohio State University Comprehensive Cancer Center
RECRUITINGColumbus, Ohio, 43210, United States
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OhioHealth Mansfield Hospital
RECRUITINGMansfield, Ohio, 44903, United States
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OhioHealth Marion General Hospital
RECRUITINGMarion, Ohio, 43302, United States
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OhioHealth O'Bleness Hospital
RECRUITINGAthens, Ohio, 45701, United States
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OhioHealth Pickerington Methodist Hospital
RECRUITINGPickerington, Ohio, 43147, United States
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OhioHealth Westerville Medical Campus/Westerville Cancer Center
RECRUITINGWesterville, Ohio, 43082, United States
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Oncology Associates at Mercy Medical Center
RECRUITINGCedar Rapids, Iowa, 52403, United States
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Park Nicollet Clinic - Saint Louis Park
RECRUITINGSaint Louis Park, Minnesota, 55416, United States
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Parkland Health Center - Farmington
RECRUITINGFarmington, Missouri, 63640, United States
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ProHealth D N Greenwald Center
SUSPENDEDMukwonago, Wisconsin, 53149, United States
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ProHealth Oconomowoc Memorial Hospital
SUSPENDEDOconomowoc, Wisconsin, 53066, United States
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Providence Newberg Medical Center
RECRUITINGNewberg, Oregon, 97132, United States
Contact Email: •••••@•••••
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Providence Portland Medical Center
RECRUITINGPortland, Oregon, 97213, United States
Contact Email: •••••@•••••
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Providence Saint Vincent Medical Center
RECRUITINGPortland, Oregon, 97225, United States
Contact Email: •••••@•••••
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Providence Willamette Falls Medical Center
RECRUITINGOregon City, Oregon, 97045, United States
Contact Email: •••••@•••••
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Regions Hospital
RECRUITINGSaint Paul, Minnesota, 55101, United States
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Riverside Methodist Hospital
RECRUITINGColumbus, Ohio, 43214, United States
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Saint Alphonsus Cancer Care Center-Baker City
RECRUITINGBaker City, Oregon, 97814, United States
Contact Email: •••••@•••••
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Saint Alphonsus Cancer Care Center-Boise
RECRUITINGBoise, Idaho, 83706, United States
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Saint Alphonsus Cancer Care Center-Caldwell
RECRUITINGCaldwell, Idaho, 83605, United States
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Saint Alphonsus Cancer Care Center-Nampa
RECRUITINGNampa, Idaho, 83687, United States
Contact Email: •••••@•••••
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Saint Alphonsus Cancer Care Center-Ontario
RECRUITINGOntario, Oregon, 97914, United States
Contact Email: •••••@•••••
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Saint Anthony Regional Hospital
RECRUITINGCarroll, Iowa, 51401, United States
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Saint Francis Medical Center
RECRUITINGCape Girardeau, Missouri, 63703, United States
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Saint Vincent Hospital Cancer Center Green Bay
RECRUITINGGreen Bay, Wisconsin, 54301, United States
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Saint Vincent Hospital Cancer Center at Oconto Falls
RECRUITINGOconto Falls, Wisconsin, 54154, United States
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Saint Vincent Hospital Cancer Center at Saint Mary's
RECRUITINGGreen Bay, Wisconsin, 54303, United States
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Saint Vincent Hospital Cancer Center at Sturgeon Bay
RECRUITINGSturgeon Bay, Wisconsin, 54235-1495, United States
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Sainte Genevieve County Memorial Hospital
RECRUITINGSainte Genevieve, Missouri, 63670, United States
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Salina Regional Health Center
RECRUITINGSalina, Kansas, 67401, United States
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Sanford Bismarck Medical Center
RECRUITINGBismarck, North Dakota, 58501, United States
Contact Email: •••••@•••••
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Sanford Broadway Medical Center
RECRUITINGFargo, North Dakota, 58122, United States
Contact Email: •••••@•••••
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Sanford Cancer Center Oncology Clinic
RECRUITINGSioux Falls, South Dakota, 57104, United States
Contact Email: •••••@•••••
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Sanford Joe Lueken Cancer Center
RECRUITINGBemidji, Minnesota, 56601, United States
Contact Email: •••••@•••••
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Sanford Roger Maris Cancer Center
RECRUITINGFargo, North Dakota, 58122, United States
Contact Email: •••••@•••••
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Sanford USD Medical Center - Sioux Falls
RECRUITINGSioux Falls, South Dakota, 57117-5134, United States
Contact Email: •••••@•••••
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Sidney Kimmel Cancer Center Washington Township
RECRUITINGSewell, New Jersey, 08080, United States
Contact Email: •••••@•••••
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Siteman Cancer Center at Christian Hospital
RECRUITINGSt Louis, Missouri, 63136, United States
Contact Email: •••••@•••••
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Siteman Cancer Center at Saint Peters Hospital
RECRUITINGCity of Saint Peters, Missouri, 63376, United States
Contact Email: •••••@•••••
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Siteman Cancer Center at West County Hospital
RECRUITINGCreve Coeur, Missouri, 63141, United States
Contact Email: •••••@•••••
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Siteman Cancer Center-South County
RECRUITINGSt Louis, Missouri, 63129, United States
Contact Email: •••••@•••••
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Southern Illinois University School of Medicine
RECRUITINGSpringfield, Illinois, 62702, United States
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Springfield Clinic
RECRUITINGSpringfield, Illinois, 62702, United States
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Springfield Memorial Hospital
RECRUITINGSpringfield, Illinois, 62781, United States
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Swedish Cancer Institute-Edmonds
RECRUITINGEdmonds, Washington, 98026, United States
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Swedish Cancer Institute-Issaquah
SUSPENDEDIssaquah, Washington, 98029, United States
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Swedish Medical Center-First Hill
RECRUITINGSeattle, Washington, 98122, United States
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The James Graham Brown Cancer Center at University of Louisville
RECRUITINGLouisville, Kentucky, 40202, United States
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The University of Kansas Cancer Center - Olathe
RECRUITINGOlathe, Kansas, 66061, United States
Contact Email: •••••@•••••
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The Watson Clinic
RECRUITINGLakeland, Florida, 33805, United States
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Thomas Jefferson University Hospital
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact Email: •••••@•••••
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Trinity Health IHA Medical Group Hematology Oncology - Brighton
RECRUITINGBrighton, Michigan, 48114, United States
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Trinity Health IHA Medical Group Hematology Oncology - Canton
RECRUITINGCanton, Michigan, 48188, United States
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Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
RECRUITINGChelsea, Michigan, 48118, United States
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Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
RECRUITINGYpsilanti, Michigan, 48197, United States
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Trinity Health Saint Joseph Mercy Oakland Hospital
RECRUITINGPontiac, Michigan, 48341, United States
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Trinity Health Saint Mary Mercy Livonia Hospital
RECRUITINGLivonia, Michigan, 48154, United States
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UI Health Care Mission Cancer and Blood - Ankeny Clinic
RECRUITINGAnkeny, Iowa, 50023, United States
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UI Health Care Mission Cancer and Blood - Des Moines Clinic
RECRUITINGDes Moines, Iowa, 50309, United States
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UI Health Care Mission Cancer and Blood - Laurel Clinic
RECRUITINGDes Moines, Iowa, 50314, United States
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UI Health Care Mission Cancer and Blood - Waukee Clinic
RECRUITINGWaukee, Iowa, 50263, United States
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UI Health Care Mission Cancer and Blood - West Des Moines Clinic
RECRUITINGClive, Iowa, 50325, United States
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UI Healthcare Mission Cancer and Blood - Fort Dodge
RECRUITINGFort Dodge, Iowa, 50501, United States
Contact Email: •••••@•••••
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UI Healthcare Mission Cancer and Blood - Pella
RECRUITINGPella, Iowa, 50219, United States
Contact Email: •••••@•••••
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UM Sylvester Comprehensive Cancer Center at Coral Gables
RECRUITINGCoral Gables, Florida, 33146, United States
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UM Sylvester Comprehensive Cancer Center at Coral Springs
RECRUITINGCoral Springs, Florida, 33065, United States
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UM Sylvester Comprehensive Cancer Center at Deerfield Beach
RECRUITINGDeerfield Beach, Florida, 33442, United States
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UM Sylvester Comprehensive Cancer Center at Doral
RECRUITINGDoral, Florida, 33166, United States
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UM Sylvester Comprehensive Cancer Center at Hollywood
RECRUITINGHollywood, Florida, 33021, United States
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UM Sylvester Comprehensive Cancer Center at Kendall
RECRUITINGMiami, Florida, 33176, United States
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UM Sylvester Comprehensive Cancer Center at Plantation
RECRUITINGPlantation, Florida, 33324, United States
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UNC Lineberger Comprehensive Cancer Center
RECRUITINGChapel Hill, North Carolina, 27599, United States
Contact Email: •••••@•••••
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UW Cancer Center at ProHealth Care
SUSPENDEDWaukesha, Wisconsin, 53188, United States
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United Hospital
RECRUITINGSaint Paul, Minnesota, 55102, United States
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University Health Truman Medical Center
RECRUITINGKansas City, Missouri, 64108, United States
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University of Alabama at Birmingham Cancer Center
RECRUITINGBirmingham, Alabama, 35233, United States
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University of Illinois
RECRUITINGChicago, Illinois, 60612, United States
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University of Kansas Cancer Center
RECRUITINGKansas City, Kansas, 66160, United States
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University of Kansas Cancer Center - Briarcliff
RECRUITINGKansas City, Missouri, 64116, United States
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University of Kansas Cancer Center - Lee's Summit
RECRUITINGLee's Summit, Missouri, 64064, United States
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University of Kansas Cancer Center - North
RECRUITINGKansas City, Missouri, 64154, United States
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University of Kansas Cancer Center-Overland Park
RECRUITINGOverland Park, Kansas, 66210, United States
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University of Kansas Health System Saint Francis Campus
RECRUITINGTopeka, Kansas, 66606, United States
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University of Kansas Hospital-Westwood Cancer Center
RECRUITINGWestwood, Kansas, 66205, United States
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University of Miami Miller School of Medicine-Sylvester Cancer Center
RECRUITINGMiami, Florida, 33136, United States
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University of Miami Sylvester Comprehensive Cancer Center at Sole Mia
RECRUITINGNorth Miami, Florida, 33181, United States
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University of Michigan Health - Sparrow Lansing
RECRUITINGLansing, Michigan, 48912, United States
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University of Oklahoma Health Sciences Center
RECRUITINGOklahoma City, Oklahoma, 73104, United States
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University of Rochester
RECRUITINGRochester, New York, 14642, United States
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UofL Health Medical Center Northeast
RECRUITINGLouisville, Kentucky, 40245, United States
Contact Email: •••••@•••••
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Email: •••••@•••••
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William S Middleton VA Medical Center
RECRUITINGMadison, Wisconsin, 53705, United States
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Wilmot Cancer Institute at Webster
RECRUITINGWebster, New York, 14580, United States
Contact Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Two-Drug combo aims to push CLL into deep remission
- Can a new BTK inhibitor outsmart resistance in CLL?
- Can a new pill outsmart Drug-Resistant leukemia?
- Can engineered immune cells beat tough B-Cell cancers?
- Can a targeted drug outperform chemo for a common blood cancer?
- Can a triple drug combo outsmart High-Risk CLL?