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Triple-Drug attack aims to wipe out CLL in new trial

NCT ID NCT03824483

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 20 times

Summary

This study tests a combination of three drugs (zanubrutinib, obinutuzumab, and venetoclax) in people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have not had prior treatment. The goal is to see if the combo can make the cancer undetectable in the bone marrow and blood. About 230 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Massachusetts General Hospital (Data Collection and Specimen Analysis)

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

    Contact

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Commack

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Monmouth

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Nassau

    RECRUITING

    Uniondale, New York, 11553, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Westchester

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering at Basking Ridge

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

  • Northwestern University

    RECRUITING

    Evanston, Illinois, 60208, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.