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New hope for Tough-to-Treat blood cancers: phase 3 trial launches

NCT ID NCT07516093

First seen Apr 21, 2026 · Last updated May 19, 2026 · Updated 3 times

Summary

This study tests a new drug, NX-5948, against another drug, pirtobrutinib, in people with chronic lymphocytic leukemia or small lymphocytic lymphoma that has returned or stopped responding to prior treatment. About 620 adults whose cancer progressed after a previous BTK inhibitor therapy will be randomly assigned to one of the two drugs. The main goal is to see which drug better delays cancer growth or death.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Conditions

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